TAOK2

TAO kinase 2
File:PBB Protein TAOK2 image.jpg PDB rendering based on 1u5q.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1u5q​, 1u5r​, 2gcd​
Identifiers
Symbols	TAOK2 ; KIAA0881; MAP3K17; PSK; PSK1; TAO1; TAO2
External IDs	HomoloGene: 74531
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TAOK2 204878 s at tn.png
File:PBB GE TAOK2 204877 s at tn.png
File:PBB GE TAOK2 204986 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

TAO kinase 2, also known as TAOK2, is a human gene.

Further reading

• Hutchison M, Berman KS, Cobb MH (1998). "Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades". J. Biol. Chem. 273 (44): 28625–32. PMID 9786855.CS1 maint: Multiple names: authors list (link)
• Nagase T, Ishikawa K, Suyama M; et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. PMID 10048485.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen Z, Hutchison M, Cobb MH (1999). "Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain". J. Biol. Chem. 274 (40): 28803–7. PMID 10497253.CS1 maint: Multiple names: authors list (link)
• Moore TM, Garg R, Johnson C; et al. (2000). "PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization". J. Biol. Chem. 275 (6): 4311–22. PMID 10660600.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen Z, Cobb MH (2001). "Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2". J. Biol. Chem. 276 (19): 16070–5. doi:10.1074/jbc.M100681200. PMID 11279118.
• Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMID 12421765.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mitsopoulos C, Zihni C, Garg R; et al. (2003). "The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability". J. Biol. Chem. 278 (20): 18085–91. doi:10.1074/jbc.M213064200. PMID 12639963.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen Z, Raman M, Chen L; et al. (2003). "TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors". J. Biol. Chem. 278 (25): 22278–83. doi:10.1074/jbc.M301173200. PMID 12665513.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yustein JT, Xia L, Kahlenburg JM; et al. (2003). "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38". Oncogene. 22 (40): 6129–41. doi:10.1038/sj.onc.1206605. PMID 13679851.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Huangfu WC, Omori E, Akira S; et al. (2006). "Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways". J. Biol. Chem. 281 (39): 28802–10. doi:10.1074/jbc.M603627200. PMID 16893890.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zihni C, Mitsopoulos C, Tavares IA; et al. (2007). "Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing". J. Biol. Chem. 282 (9): 6484–93. doi:10.1074/jbc.M608336200. PMID 17158878.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)