GCN5L2

GCN5 general control of amino-acid synthesis 5-like 2 (yeast)
PDB rendering based on 1f68.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1f68​, 1z4r​
Identifiers
Symbols	GCN5L2 ; GCN5; MGC102791; PCAF-b; hGCN5
External IDs	Template:OMIM5 Template:MGI HomoloGene: 41343
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

GCN5 general control of amino-acid synthesis 5-like 2 (yeast), also known as GCN5L2, is a human gene.

Further reading

• Berry R, Stevens TJ, Walter NA; et al. (1995). "Gene-based sequence-tagged-sites (STSs) as the basis for a human gene map". Nat. Genet. 10 (4): 415–23. doi:10.1038/ng0895-415. PMID 7670491.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Candau R, Moore PA, Wang L; et al. (1996). "Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5". Mol. Cell. Biol. 16 (2): 593–602. PMID 8552087.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yang XJ, Ogryzko VV, Nishikawa J; et al. (1996). "A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A". Nature. 382 (6589): 319–24. doi:10.1038/382319a0. PMID 8684459.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang L, Mizzen C, Ying C; et al. (1997). "Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation". Mol. Cell. Biol. 17 (1): 519–27. PMID 8972232.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Carter KC, Wang L, Shell BK; et al. (1997). "The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern". Genomics. 40 (3): 497–500. doi:10.1006/geno.1996.4605. PMID 9073520.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Barlev NA, Poltoratsky V, Owen-Hughes T; et al. (1998). "Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex". Mol. Cell. Biol. 18 (3): 1349–58. PMID 9488450.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Smith ER, Belote JM, Schiltz RL; et al. (1998). "Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members". Nucleic Acids Res. 26 (12): 2948–54. PMID 9611240.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Randhawa GS, Bell DW, Testa JR, Feinberg AP (1998). "Identification and mapping of human histone acetylation modifier gene homologues". Genomics. 51 (2): 262–9. doi:10.1006/geno.1998.5370. PMID 9722949.CS1 maint: Multiple names: authors list (link)
• Xu W, Edmondson DG, Roth SY (1998). "Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates". Mol. Cell. Biol. 18 (10): 5659–69. PMID 9742083.CS1 maint: Multiple names: authors list (link)
• Brand M, Yamamoto K, Staub A, Tora L (1999). "Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction". J. Biol. Chem. 274 (26): 18285–9. PMID 10373431.CS1 maint: Multiple names: authors list (link)
• McMahon SB, Wood MA, Cole MD (2000). "The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc". Mol. Cell. Biol. 20 (2): 556–62. PMID 10611234.CS1 maint: Multiple names: authors list (link)
• Kurooka H, Honjo T (2000). "Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5". J. Biol. Chem. 275 (22): 17211–20. doi:10.1074/jbc.M000909200. PMID 10747963.
• Hudson BP, Martinez-Yamout MA, Dyson HJ, Wright PE (2000). "Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain". J. Mol. Biol. 304 (3): 355–70. doi:10.1006/jmbi.2000.4207. PMID 11090279.CS1 maint: Multiple names: authors list (link)
• Col E, Caron C, Seigneurin-Berny D; et al. (2001). "The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat". J. Biol. Chem. 276 (30): 28179–84. doi:10.1074/jbc.M101385200. PMID 11384967.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brand M, Moggs JG, Oulad-Abdelghani M; et al. (2001). "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation". EMBO J. 20 (12): 3187–96. doi:10.1093/emboj/20.12.3187. PMID 11406595.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gangloff YG, Pointud JC, Thuault S; et al. (2001). "The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger". Mol. Cell. Biol. 21 (15): 5109–21. doi:10.1128/MCB.21.15.5109-5121.2001. PMID 11438666.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martinez E, Palhan VB, Tjernberg A; et al. (2001). "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo". Mol. Cell. Biol. 21 (20): 6782–95. doi:10.1128/MCB.21.20.6782-6795.2001. PMID 11564863.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yanagisawa J, Kitagawa H, Yanagida M; et al. (2002). "Nuclear receptor function requires a TFTC-type histone acetyl transferase complex". Mol. Cell. 9 (3): 553–62. PMID 11931763.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brès V, Kiernan R, Emiliani S, Benkirane M (2002). "Tat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replication". J. Biol. Chem. 277 (25): 22215–21. doi:10.1074/jbc.M201895200. PMID 11956210.CS1 maint: Multiple names: authors list (link)
• Col E, Gilquin B, Caron C, Khochbin S (2002). "Tat-controlled protein acetylation". J. Biol. Chem. 277 (40): 37955–60. doi:10.1074/jbc.M206694200. PMID 12154097.CS1 maint: Multiple names: authors list (link)