CABLES1

Cdk5 and Abl enzyme substrate 1
Identifiers
Symbols	CABLES1 ; FLJ35924; HsT2563
External IDs	Template:OMIM5 Template:MGI HomoloGene: 11097
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Cdk5 and Abl enzyme substrate 1, also known as CABLES1, is a human gene.

CABLES1 is a cyclin-dependent kinase (CDK)-binding protein that plays a role in proliferation and/or differentiation (Zukerberg et al., 2004).[supplied by OMIM]

Further reading

• Matsuoka M, Matsuura Y, Semba K, Nishimoto I (2000). "Molecular cloning of a cyclin-like protein associated with cyclin-dependent kinase 3 (cdk 3) in vivo". Biochem. Biophys. Res. Commun. 273 (2): 442–7. doi:10.1006/bbrc.2000.2965. PMID 10873625.CS1 maint: Multiple names: authors list (link)
• Zukerberg LR, Patrick GN, Nikolic M; et al. (2000). "Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth". Neuron. 26 (3): 633–46. PMID 10896159.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamochi T, Nishimoto I, Okuda T, Matsuoka M (2001). "ik3-1/Cables is associated with Trap and Pctaire2". Biochem. Biophys. Res. Commun. 286 (5): 1045–50. doi:10.1006/bbrc.2001.5493. PMID 11527406.CS1 maint: Multiple names: authors list (link)
• Wu CL, Kirley SD, Xiao H; et al. (2001). "Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers". Cancer Res. 61 (19): 7325–32. PMID 11585773.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tsuji K, Mizumoto K, Yamochi T; et al. (2002). "Differential effect of ik3-1/cables on p53- and p73-induced cell death". J. Biol. Chem. 277 (4): 2951–7. doi:10.1074/jbc.M108535200. PMID 11706030.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamochi T, Semba K, Tsuji K; et al. (2002). "ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3)". Eur. J. Biochem. 268 (23): 6076–82. PMID 11733001.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sato H, Nishimoto I, Matsuoka M (2002). "ik3-2, a relative to ik3-1/cables, is associated with cdk3, cdk5, and c-abl". Biochim. Biophys. Acta. 1574 (2): 157–63. PMID 11955625.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tan D, Kirley S, Li Q; et al. (2003). "Loss of cables protein expression in human non-small cell lung cancer: a tissue microarray study". Hum. Pathol. 34 (2): 143–9. doi:10.1053/hupa.2003.26. PMID 12612882.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dong Q, Kirley S, Rueda B; et al. (2004). "Loss of cables, a novel gene on chromosome 18q, in ovarian cancer". Mod. Pathol. 16 (9): 863–8. doi:10.1097/01.MP.0000084434.88269.0A. PMID 13679449.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Matsuoka M, Sudo H, Tsuji K; et al. (2004). "ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways". Biochem. Biophys. Res. Commun. 312 (2): 520–9. PMID 14637168.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zukerberg LR, DeBernardo RL, Kirley SD; et al. (2004). "Loss of cables, a cyclin-dependent kinase regulatory protein, is associated with the development of endometrial hyperplasia and endometrial cancer". Cancer Res. 64 (1): 202–8. PMID 14729625.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang H, Duan HO, Kirley SD; et al. (2006). "Aberrant splicing of cables gene, a CDK regulator, in human cancers". Cancer Biol. Ther. 4 (11): 1211–5. PMID 16177568.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nusbaum C, Zody MC, Borowsky ML; et al. (2005). "DNA sequence and analysis of human chromosome 18". Nature. 437 (7058): 551–5. doi:10.1038/nature03983. PMID 16177791.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hirao N, Sato S, Gotoh T; et al. (2007). "NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation". FEBS Lett. 580 (27): 6464–70. doi:10.1016/j.febslet.2006.10.065. PMID 17101133.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)