RIT2

Ras-like without CAAX 2
Identifiers
Symbols	RIT2 ; RIBA; RIN; ROC2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2198
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RIT2 206984 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Ras-like without CAAX 2, also known as RIT2, is a human gene.

RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999).[supplied by OMIM]

Further reading

• Lee CH, Della NG, Chew CE, Zack DJ (1996). "Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins". J. Neurosci. 16 (21): 6784–94. PMID 8824319.CS1 maint: Multiple names: authors list (link)
• Wes PD, Yu M, Montell C (1997). "RIC, a calmodulin-binding Ras-like GTPase". EMBO J. 15 (21): 5839–48. PMID 8918462.CS1 maint: Multiple names: authors list (link)
• Shao H, Kadono-Okuda K, Finlin BS, Andres DA (1999). "Biochemical characterization of the Ras-related GTPases Rit and Rin". Arch. Biochem. Biophys. 371 (2): 207–19. doi:10.1006/abbi.1999.1448. PMID 10545207.CS1 maint: Multiple names: authors list (link)
• Hoshino M, Nakamura S (2002). "The Ras-like small GTP-binding protein Rin is activated by growth factor stimulation". Biochem. Biophys. Res. Commun. 295 (3): 651–6. PMID 12099688.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Calissano M, Latchman DS (2003). "Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor". Oncogene. 22 (35): 5408–14. doi:10.1038/sj.onc.1206635. PMID 12934100.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hartwig C, Veske A, Krejcova S; et al. (2006). "Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin". BMC neuroscience. 6: 53. doi:10.1186/1471-2202-6-53. PMID 16122393.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shi GX, Han J, Andres DA (2006). "Rin GTPase couples nerve growth factor signaling to p38 and b-Raf/ERK pathways to promote neuronal differentiation". J. Biol. Chem. 280 (45): 37599–609. doi:10.1074/jbc.M507364200. PMID 16157584.CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)