RRAS

Related RAS viral (r-ras) oncogene homolog
File:PBB Protein RRAS image.jpg PDB rendering based on 2fn4.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2fn4​
Identifiers
Symbols	RRAS ;
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4565
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE RRAS 212647 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Related RAS viral (r-ras) oncogene homolog, also known as RRAS, is a human gene.

Further reading

• Lowe DG, Capon DJ, Delwart E; et al. (1987). "Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes". Cell. 48 (1): 137–46. PMID 3098437.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Carboni JM, Yan N, Cox AD; et al. (1995). "Farnesyltransferase inhibitors are inhibitors of Ras but not R-Ras2/TC21, transformation". Oncogene. 10 (10): 1905–13. PMID 7761092.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Spaargaren M, Bischoff JR (1995). "Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap". Proc. Natl. Acad. Sci. U.S.A. 91 (26): 12609–13. PMID 7809086.
• Fernandez-Sarabia MJ, Bischoff JR (1993). "Bcl-2 associates with the ras-related protein R-ras p23". Nature. 366 (6452): 274–5. doi:10.1038/366274a0. PMID 8232588.
• Linnemann T, Geyer M, Jaitner BK; et al. (1999). "Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily". J. Biol. Chem. 274 (19): 13556–62. PMID 10224125.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Choy E, Chiu VK, Silletti J; et al. (1999). "Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi". Cell. 98 (1): 69–80. doi:10.1016/S0092-8674(00)80607-8. PMID 10412982.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zou JX, Wang B, Kalo MS; et al. (2000). "An Eph receptor regulates integrin activity through R-Ras". Proc. Natl. Acad. Sci. U.S.A. 96 (24): 13813–8. PMID 10570155.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang B, Zou JX, Ek-Rylander B, Ruoslahti E (2000). "R-Ras contains a proline-rich site that binds to SH3 domains and is required for integrin activation by R-Ras". J. Biol. Chem. 275 (7): 5222–7. PMID 10671570.CS1 maint: Multiple names: authors list (link)
• Suzuki J, Kaziro Y, Koide H (2000). "Positive regulation of skeletal myogenesis by R-Ras". Oncogene. 19 (9): 1138–46. doi:10.1038/sj.onc.1203402. PMID 10713701.CS1 maint: Multiple names: authors list (link)
• Ohba Y, Mochizuki N, Yamashita S; et al. (2000). "Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3". J. Biol. Chem. 275 (26): 20020–6. doi:10.1074/jbc.M000981200. PMID 10777492.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yuryev A, Ono M, Goff SA; et al. (2000). "Isoform-specific localization of A-RAF in mitochondria". Mol. Cell. Biol. 20 (13): 4870–8. PMID 10848612.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Oertli B, Han J, Marte BM; et al. (2000). "The effector loop and prenylation site of R-Ras are involved in the regulation of integrin function". Oncogene. 19 (43): 4961–9. doi:10.1038/sj.onc.1203876. PMID 11042683.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tian X, Feig LA (2002). "Basis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factors". J. Biol. Chem. 276 (50): 47248–56. doi:10.1074/jbc.M107407200. PMID 11560935.
• Ortiz-Vega S, Khokhlatchev A, Nedwidek M; et al. (2002). "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. 21 (9): 1381–90. doi:10.1038/sj.onc.1205192. PMID 11857081.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu Y, Feig LA (2002). "Involvement of R-Ras and Ral GTPases in estrogen-independent proliferation of breast cancer cells". Oncogene. 21 (49): 7557–68. doi:10.1038/sj.onc.1205961. PMID 12386818.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kwong L, Wozniak MA, Collins AS; et al. (2003). "R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins". Mol. Cell. Biol. 23 (3): 933–49. PMID 12529399.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rincón-Arano H, Rosales R, Mora N; et al. (2003). "R-Ras promotes tumor growth of cervical epithelial cells". Cancer. 97 (3): 575–85. doi:10.1002/cncr.11093. PMID 12548599.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Furuhjelm J, Peränen J (2004). "The C-terminal end of R-Ras contains a focal adhesion targeting signal". J. Cell. Sci. 116 (Pt 18): 3729–38. doi:10.1242/jcs.00689. PMID 12890755.
• Mitin NY, Ramocki MB, Zullo AJ; et al. (2004). "Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization". J. Biol. Chem. 279 (21): 22353–61. doi:10.1074/jbc.M312867200. PMID 15031288.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)