SGTA
| Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SGTA ; SGT; hSGT | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 31122 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SGTA 201396 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha, also known as SGTA, is a human gene.[1]
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.[1]
References
Further reading
- Heavner GA, Audhya T, Goldstein G (1990). "Peptide analogs of thymopentin distinguish distinct thymopoietin receptor specificities on two human T cell lines". Regul. Pept. 27 (2): 257–62. PMID 2158125.
- Geraghty RJ, Talbot KJ, Callahan M; et al. (1994). "Cell type-dependence for Vpu function". J. Med. Primatol. 23 (2–3): 146–50. PMID 7966229.
- Cziepluch C, Kordes E, Poirey R; et al. (1998). "Identification of a novel cellular TPR-containing protein, SGT, that interacts with the nonstructural protein NS1 of parvovirus H-1". J. Virol. 72 (5): 4149–56. PMID 9557704.
- Callahan MA, Handley MA, Lee YH; et al. (1998). "Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family". J. Virol. 72 (6): 5189–97. PMID 9573291.
- Kordes E, Savelyeva L, Schwab M; et al. (1999). "Isolation and characterization of human SGT and identification of homologues in Saccharomyces cerevisiae and Caenorhabditis elegans". Genomics. 52 (1): 90–4. doi:10.1006/geno.1998.5385. PMID 9740675.
- Callahan MA, Handley MA, Lee YH; et al. (1998). "Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family". J. Virol. 72 (10): 8461. PMID 9766974.
- Liu FH, Wu SJ, Hu SM; et al. (1999). "Specific interaction of the 70-kDa heat shock cognate protein with the tetratricopeptide repeats". J. Biol. Chem. 274 (48): 34425–32. PMID 10567422.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
- Handley MA, Paddock S, Dall A, Panganiban AT (2002). "Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag protein". Virology. 291 (2): 198–207. doi:10.1006/viro.2001.1166. PMID 11878889.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Angeletti PC, Walker D, Panganiban AT (2003). "Small glutamine-rich protein/viral protein U-binding protein is a novel cochaperone that affects heat shock protein 70 activity". Cell Stress Chaperones. 7 (3): 258–68. PMID 12482202.
- Schantl JA, Roza M, De Jong AP, Strous GJ (2003). "Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent endocytosis (UbE) motif of the growth hormone receptor". Biochem. J. 373 (Pt 3): 855–63. doi:10.1042/BJ20021591. PMID 12735788.
- Pai MT, Yang CS, Tzeng SR; et al. (2004). "1H, 15N and 13C resonance assignments of the tetratricopeptide repeat (TPR) domain of hSGT". J. Biomol. NMR. 26 (4): 381–2. PMID 12815268.
- Wang H, Zhang Q, Zhu D (2004). "hSGT interacts with the N-terminal region of myostatin". Biochem. Biophys. Res. Commun. 311 (4): 877–83. PMID 14623262.
- Lehner B, Semple JI, Brown SE; et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. PMID 14667819.
- Winnefeld M, Rommelaere J, Cziepluch C (2004). "The human small glutamine-rich TPR-containing protein is required for progress through cell division". Exp. Cell Res. 293 (1): 43–57. PMID 14729056.
- Grimwood J, Gordon LA, Olsen A; et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
- Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
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