FSTL3
| Follistatin-like 3 (secreted glycoprotein) | |||||||||||
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| Identifiers | |||||||||||
| Symbols | FSTL3 ; FLRG; FSRP | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 4280 | ||||||||||
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| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
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| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
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Follistatin-like 3 (secreted glycoprotein), also known as FSTL3, is a human gene.[1]
Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis.[1]
References
Further reading
- Maguer-Satta V, Rimokh R (2005). "FLRG, member of the follistatin family, a new player in hematopoiesis". Mol. Cell. Endocrinol. 225 (1–2): 109–18. doi:10.1016/j.mce.2004.07.009. PMID 15451575.
- Hayette S, Gadoux M, Martel S; et al. (1998). "FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders". Oncogene. 16 (22): 2949–54. doi:10.1038/sj.onc.1201807. PMID 9671416.
- Dias Neto E, Correa RG, Verjovski-Almeida S; et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. PMID 10737800.
- Tortoriello DV, Sidis Y, Holtzman DA; et al. (2001). "Human follistatin-related protein: a structural homologue of follistatin with nuclear localization". Endocrinology. 142 (8): 3426–34. PMID 11459787.
- Bartholin L, Maguer-Satta V, Hayette S; et al. (2001). "FLRG, an activin-binding protein, is a new target of TGFbeta transcription activation through Smad proteins". Oncogene. 20 (39): 5409–19. doi:10.1038/sj.onc.1204720. PMID 11571638.
- Bartholin L, Maguer-Satta V, Hayette S; et al. (2002). "Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function". Oncogene. 21 (14): 2227–35. doi:10.1038/sj.onc.1205294. PMID 11948405.
- Hill JJ, Davies MV, Pearson AA; et al. (2002). "The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum". J. Biol. Chem. 277 (43): 40735–41. doi:10.1074/jbc.M206379200. PMID 12194980.
- Liu J, Vänttinen T, Hydén-Granskog C, Voutilainen R (2003). "Regulation of follistatin-related gene (FLRG) expression by protein kinase C and prostaglandin E(2) in cultured granulosa-luteal cells". Mol. Hum. Reprod. 8 (11): 992–7. PMID 12397211.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Maguer-Satta V, Bartholin L, Jeanpierre S; et al. (2003). "Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGFbeta family". Exp. Cell Res. 282 (2): 110–20. PMID 12531697.
- Wang HQ, Takebayashi K, Tsuchida K; et al. (2003). "Follistatin-related gene (FLRG) expression in human endometrium: sex steroid hormones regulate the expression of FLRG in cultured human endometrial stromal cells". J. Clin. Endocrinol. Metab. 88 (9): 4432–9. PMID 12970321.
- Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
- Xia Y, Sidis Y, Schneyer A (2004). "Overexpression of follistatin-like 3 in gonads causes defects in gonadal development and function in transgenic mice". Mol. Endocrinol. 18 (4): 979–94. doi:10.1210/me.2003-0364. PMID 14739256.
- Florio P, Ciarmela P, Toti P; et al. (2004). "Human endometrium and decidua express follistatin-related gene (FLRG) mRNA and peptide". Mol. Cell. Endocrinol. 218 (1–2): 129–35. doi:10.1016/j.mce.2003.12.019. PMID 15130517.
- Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Glusman G, Kaur A, Hood L, Rowen L (2005). "An enigmatic fourth runt domain gene in the fugu genome: ancestral gene loss versus accelerated evolution". BMC Evol. Biol. 4: 43. doi:10.1186/1471-2148-4-43. PMID 15527507.
- Saito S, Sidis Y, Mukherjee A; et al. (2006). "Differential biosynthesis and intracellular transport of follistatin isoforms and follistatin-like-3". Endocrinology. 146 (12): 5052–62. doi:10.1210/en.2005-0833. PMID 16150905.
- Okamoto A, Endo H, Kalionis B; et al. (2006). "IGFBP1 and Follistatin-like 3 genes are significantly up-regulated in expression profiles of the IUGR placenta". Placenta. 27 (2–3): 317–21. doi:10.1016/j.placenta.2004.12.007. PMID 16338475.
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