CLEC11A
| C-type lectin domain family 11, member A | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | CLEC11A ; P47; CLECSF3; LSLCL; SCGF | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 2236 | ||||||||||
| |||||||||||
| RNA expression pattern | |||||||||||
 | |||||||||||
 | |||||||||||
 | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
C-type lectin domain family 11, member A, also known as CLEC11A, is a human gene.[1]
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.[1]
References
Further reading
- Hiraoka A, Ohkubo T, Fukuda M (1987). "Production of human hematopoietic survival and growth factor by a myeloid leukemia cell line (KPB-M15) and placenta as detected by a monoclonal antibody". Cancer Res. 47 (19): 5025–30. PMID 3304620.
- Hiraoka A, Sugimura A, Seki T; et al. (1997). "Cloning, expression, and characterization of a cDNA encoding a novel human growth factor for primitive hematopoietic progenitor cells". Proc. Natl. Acad. Sci. U.S.A. 94 (14): 7577–82. PMID 9207134.
- Bannwarth S, Giordanengo V, Lesimple J, Lefebvre JC (1998). "Molecular cloning of a new secreted sulfated mucin-like protein with a C-type lectin domain that is expressed in lymphoblastic cells". J. Biol. Chem. 273 (4): 1911–6. PMID 9442024.
- Mio H, Kagami N, Yokokawa S; et al. (1998). "Isolation and characterization of a cDNA for human mouse, and rat full-length stem cell growth factor, a new member of C-type lectin superfamily". Biochem. Biophys. Res. Commun. 249 (1): 124–30. doi:10.1006/bbrc.1998.9073. PMID 9705843.
- Bannwarth S, Giordanengo V, Grosgeorge J; et al. (1999). "Cloning, mapping, and genomic organization of the LSLCL gene, encoding a new lymphocytic secreted mucin-like protein with a C-type lectin domain: A new model of exon shuffling". Genomics. 57 (2): 316–7. doi:10.1006/geno.1999.5762. PMID 10198175.
- Gehling UM, Ergün S, Schumacher U; et al. (2000). "In vitro differentiation of endothelial cells from AC133-positive progenitor cells". Blood. 95 (10): 3106–12. PMID 10807776.
- Perrin C, Bayle J, Bannwarth S; et al. (2002). "Expression of LSLCL, a new C-type lectin, is closely restricted, in bone marrow, to immature neutrophils". C. R. Acad. Sci. III, Sci. Vie. 324 (12): 1125–32. PMID 11803813.
- Hiraoka A, Yano Ki K, Kagami N; et al. (2002). "Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells". Hematol. J. 2 (5): 307–15. doi:10.1038/sj/thj/6200118. PMID 11920266.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ito C, Sato H, Ando K; et al. (2004). "Serum stem cell growth factor for monitoring hematopoietic recovery following stem cell transplantation". Bone Marrow Transplant. 32 (4): 391–8. doi:10.1038/sj.bmt.1704152. PMID 12900775.
- Lee E, Min HK, Oskeritzian CA; et al. (2004). "Recombinant human (rh) stem cell factor and rhIL-4 stimulate differentiation and proliferation of CD3+ cells from umbilical cord blood and CD3+ cells enhance FcepsilonR1 expression on fetal liver-derived mast cells in the presence of rhIL-4". Cell. Immunol. 226 (1): 30–6. PMID 14746805.
- Hollenbeck ST, Sakakibara K, Faries PL; et al. (2004). "Stem cell factor and c-kit are expressed by and may affect vascular SMCs through an autocrine pathway". J. Surg. Res. 120 (2): 288–94. doi:10.1016/j.jss.2004.01.005. PMID 15234225.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
 | This protein-related article is a stub. You can help Wikipedia by expanding it. |