AKT1S1

AKT1 substrate 1 (proline-rich)
Identifiers
Symbols	AKT1S1 ; Lobe; MGC2865; PRAS40
External IDs	Template:OMIM5 Template:MGI HomoloGene: 12162
Gene ontology Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

AKT1 substrate 1 (proline-rich), also known as AKT1S1, is a human gene.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kovacina KS, Park GY, Bae SS; et al. (2003). "Identification of a proline-rich Akt substrate as a 14-3-3 binding partner". J. Biol. Chem. 278 (12): 10189–94. doi:10.1074/jbc.M210837200. PMID 12524439.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Saito A, Narasimhan P, Hayashi T; et al. (2004). "Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor". J. Neurosci. 24 (7): 1584–93. doi:10.1523/JNEUROSCI.5209-03.2004. PMID 14973226.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jin J, Smith FD, Stark C; et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Huang B, Porter G (2006). "Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis". Acta Pharmacol. Sin. 26 (10): 1253–8. PMID 16174443.
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vander Haar E, Lee SI, Bandhakavi S; et al. (2007). "Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40". Nat. Cell Biol. 9 (3): 316–23. doi:10.1038/ncb1547. PMID 17277771.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sancak Y, Thoreen CC, Peterson TR; et al. (2007). "PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase". Mol. Cell. 25 (6): 903–15. doi:10.1016/j.molcel.2007.03.003. PMID 17386266.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang L, Harris TE, Roth RA, Lawrence JC (2007). "PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding". J. Biol. Chem. 282 (27): 20036–44. doi:10.1074/jbc.M702376200. PMID 17510057.CS1 maint: Multiple names: authors list (link)
• Fonseca BD, Smith EM, Lee VH; et al. (2007). "PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex". J. Biol. Chem. 282 (34): 24514–24. doi:10.1074/jbc.M704406200. PMID 17604271.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)