DAPK3

Death-associated protein kinase 3
PDB rendering based on 1yrp.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1yrp​, 2j90​
Identifiers
Symbols	DAPK3 ; FLJ36473; ZIP; ZIPK
External IDs	Template:OMIM5 Template:MGI HomoloGene: 20353
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Death-associated protein kinase 3, also known as DAPK3, is a human gene.

Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.

Further reading

• Kawai T, Matsumoto M, Takeda K; et al. (1998). "ZIP kinase, a novel serine/threonine kinase which mediates apoptosis". Mol. Cell. Biol. 18 (3): 1642–51. PMID 9488481.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Saito T, Seki N, Ohira M; et al. (1998). "Assignment of the ZIP kinase gene to human chromosome 19p13.3 by somatic hybrid analysis and fluorescence in-situ hybridization". J. Hum. Genet. 43 (3): 209–11. PMID 9747039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Murata-Hori M, Suizu F, Iwasaki T; et al. (1999). "ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells". FEBS Lett. 451 (1): 81–4. PMID 10356987.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Page G, Lödige I, Kögel D, Scheidtmann KH (2000). "AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis". FEBS Lett. 462 (1–2): 187–91. PMID 10580117.CS1 maint: Multiple names: authors list (link)
• Page G, Kögel D, Rangnekar V, Scheidtmann KH (2000). "Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis". Oncogene. 18 (51): 7265–73. doi:10.1038/sj.onc.1203170. PMID 10602480.CS1 maint: Multiple names: authors list (link)
• Cariou B, Perdereau D, Cailliau K; et al. (2002). "The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta". Mol. Cell. Biol. 22 (20): 6959–70. PMID 12242277.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Preuss U, Landsberg G, Scheidtmann KH (2003). "Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase". Nucleic Acids Res. 31 (3): 878–85. PMID 12560483.CS1 maint: Multiple names: authors list (link)
• Kawai T, Akira S, Reed JC (2003). "ZIP kinase triggers apoptosis from nuclear PML oncogenic domains". Mol. Cell. Biol. 23 (17): 6174–86. PMID 12917339.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Burch LR, Scott M, Pohler E; et al. (2004). "Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1". J. Mol. Biol. 337 (1): 115–28. doi:10.1016/j.jmb.2003.10.081. PMID 15001356.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Endo A, Surks HK, Mochizuki S; et al. (2004). "Identification and characterization of zipper-interacting protein kinase as the unique vascular smooth muscle myosin phosphatase-associated kinase". J. Biol. Chem. 279 (40): 42055–61. doi:10.1074/jbc.M403676200. PMID 15292222.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schaaf CP, Benzing J, Schmitt T; et al. (2005). "Novel interaction partners of the TPR/MET tyrosine kinase". FASEB J. 19 (2): 267–9. doi:10.1096/fj.04-1558fje. PMID 15546961.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu H, Jiang D, Guo Z; et al. (2005). "TCP10L is expressed specifically in spermatogenic cells and binds to death associated protein kinase-3". Int. J. Androl. 28 (3): 163–70. doi:10.1111/j.1365-2605.2005.00522.x. PMID 15910542.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takamoto N, Komatsu S, Komaba S; et al. (2007). "Novel ZIP kinase isoform lacks leucine zipper". Arch. Biochem. Biophys. 456 (2): 194–203. doi:10.1016/j.abb.2006.09.026. PMID 17126281.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)