SULT4A1

Sulfotransferase family 4A, member 1
File:PBB Protein SULT4A1 image.jpg PDB rendering based on 1zd1.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1zd1​
Identifiers
Symbols	SULT4A1 ; BR-STL-1; BRSTL1; DJ388M5.3; MGC40032; NST; SULTX3; hBR-STL-1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 49378
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SULT4A1 219425 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Sulfotransferase family 4A, member 1, also known as SULT4A1, is a human gene.

This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia.

Further reading

• Weinshilboum RM, Otterness DM, Aksoy IA; et al. (1997). "Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes". FASEB J. 11 (1): 3–14. PMID 9034160.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glatt H, Engelke CE, Pabel U; et al. (2000). "Sulfotransferases: genetics and role in toxicology". Toxicol. Lett. 112-113: 341–8. PMID 10720750.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glatt H (2001). "Sulfotransferases in the bioactivation of xenobiotics". Chem. Biol. Interact. 129 (1–2): 141–70. PMID 11154739.
• Glatt H, Boeing H, Engelke CE; et al. (2001). "Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects". Mutat. Res. 482 (1–2): 27–40. PMID 11535246.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dunham I, Shimizu N, Roe BA; et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Falany CN, Xie X, Wang J; et al. (2000). "Molecular cloning and expression of novel sulphotransferase-like cDNAs from human and rat brain". Biochem. J. 346 Pt 3: 857–64. PMID 10698717.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sakakibara Y, Suiko M, Pai TG; et al. (2002). "Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization". Gene. 285 (1–2): 39–47. PMID 12039030.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Collins JE, Goward ME, Cole CG; et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMID 12529303.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liyou NE, Buller KM, Tresillian MJ; et al. (2004). "Localization of a brain sulfotransferase, SULT4A1, in the human and rat brain: an immunohistochemical study". J. Histochem. Cytochem. 51 (12): 1655–64. PMID 14623933.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Collins JE, Wright CL, Edwards CA; et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brennan MD, Condra J (2006). "Transmission disequilibrium suggests a role for the sulfotransferase-4A1 gene in schizophrenia". Am. J. Med. Genet. B Neuropsychiatr. Genet. 139 (1): 69–72. doi:10.1002/ajmg.b.30222. PMID 16152568.
• Allali-Hassani A, Pan PW, Dombrovski L; et al. (2007). "Structural and chemical profiling of the human cytosolic sulfotransferases". PLoS Biol. 5 (5): e97. doi:10.1371/journal.pbio.0050097. PMID 17425406.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)