SEPT8
Septin 8 | |||||||||
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Identifiers | |||||||||
Symbols | SEPT8 ; SEP2; KIAA0202 | ||||||||
External IDs | Template:OMIM5 | ||||||||
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Orthologs | |||||||||
Template:GNF Ortholog box | |||||||||
Species | Human | Mouse | |||||||
Entrez | n/a | n/a | |||||||
Ensembl | n/a | n/a | |||||||
UniProt | n/a | n/a | |||||||
RefSeq (mRNA) | n/a | n/a | |||||||
RefSeq (protein) | n/a | n/a | |||||||
Location (UCSC) | n/a | n/a | |||||||
PubMed search | n/a | n/a |
Septin 8, also known as SEPT8, is a human gene.[1]
SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking (Blaser et al., 2003).[supplied by OMIM][1]
References
Further reading
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.
- Nagase T, Seki N, Ishikawa K; et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. PMID 9039502.
- Frazer KA, Ueda Y, Zhu Y; et al. (1997). "Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region". Genome Res. 7 (5): 495–512. PMID 9149945.
- Wenderfer SE, Slack JP, McCluskey TS, Monaco JJ (2000). "Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11". Genomics. 63 (3): 354–73. doi:10.1006/geno.1999.6100. PMID 10704283.
- Bläser S, Jersch K, Hainmann I; et al. (2002). "Human septin-septin interaction: CDCrel-1 partners with KIAA0202". FEBS Lett. 519 (1–3): 169–72. PMID 12023038.
- Yang T, Gao YK, Chen JY (2002). "KIAA0202, a human septin family member, interacting with hPFTAIRE1". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao. 34 (4): 520–5. PMID 12098780.
- Macara IG, Baldarelli R, Field CM; et al. (2003). "Mammalian septins nomenclature". Mol. Biol. Cell. 13 (12): 4111–3. doi:10.1091/mbc.E02-07-0438. PMID 12475938.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Bläser S, Jersch K, Hainmann I; et al. (2003). "Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202)". Gene. 312: 313–20. PMID 12909369.
- Bläser S, Horn J, Würmell P; et al. (2004). "The novel human platelet septin SEPT8 is an interaction partner of SEPT4". Thromb. Haemost. 91 (5): 959–66. doi:10.1267/THRO04050959. PMID 15116257.
- Martínez C, Sanjuan MA, Dent JA; et al. (2005). "Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol". Biochem. J. 382 (Pt 3): 783–91. doi:10.1042/BJ20040372. PMID 15214843.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
- Bläser S, Röseler S, Rempp H; et al. (2006). "Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5". J. Pathol. 210 (1): 103–10. doi:10.1002/path.2013. PMID 16767699.
- Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
- Xin X, Pache M, Zieger B; et al. (2007). "Septin expression in proliferative retinal membranes". J. Histochem. Cytochem. 55 (11): 1089–94. doi:10.1369/jhc.7A7188.2007. PMID 17625225.
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