TPPP

Brain-specific protein p25 alpha
Identifiers
Symbols	TPPP ; p25; p24
External IDs	Template:OMIM5 Template:MGI HomoloGene: 21389
Gene ontology
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Brain-specific protein p25 alpha, also known as TPPP, is a human gene.

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Seki N, Hattori A, Sugano S; et al. (1999). "A novel human gene whose product shares significant homology with the bovine brain-specific protein p25 on chromosome 5p15.3". J. Hum. Genet. 44 (2): 121–2. PMID 10083737.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martín CP, Vázquez J, Avila J, Moreno FJ (2002). "P24, a glycogen synthase kinase 3 (GSK 3) inhibitor". Biochim. Biophys. Acta. 1586 (1): 113–22. PMID 11781156.CS1 maint: Multiple names: authors list (link)
• Hlavanda E, Kovács J, Oláh J; et al. (2002). "Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations". Biochemistry. 41 (27): 8657–64. PMID 12093283.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tirián L, Hlavanda E, Oláh J; et al. (2004). "TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation". Proc. Natl. Acad. Sci. U.S.A. 100 (24): 13976–81. doi:10.1073/pnas.2436331100. PMID 14623963.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lehotzky A, Tirián L, Tökési N; et al. (2005). "Dynamic targeting of microtubules by TPPP/p25 affects cell survival". J. Cell. Sci. 117 (Pt 25): 6249–59. doi:10.1242/jcs.01550. PMID 15564385.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lindersson E, Lundvig D, Petersen C; et al. (2005). "p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies". J. Biol. Chem. 280 (7): 5703–15. doi:10.1074/jbc.M410409200. PMID 15590652.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• DeGiorgis JA, Jaffe H, Moreira JE; et al. (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". J. Proteome Res. 4 (2): 306–15. doi:10.1021/pr0498436. PMID 15822905.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jämsä A, Bäckström A, Gustafsson E; et al. (2006). "Glutamate treatment and p25 transfection increase Cdk5 mediated tau phosphorylation in SH-SY5Y cells". Biochem. Biophys. Res. Commun. 345 (1): 324–31. doi:10.1016/j.bbrc.2006.04.032. PMID 16678793.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Skjoerringe T, Lundvig DM, Jensen PH, Moos T (2006). "P25alpha/Tubulin polymerization promoting protein expression by myelinating oligodendrocytes of the developing rat brain". J. Neurochem. 99 (1): 333–42. doi:10.1111/j.1471-4159.2006.04073.x. PMID 16879710.CS1 maint: Multiple names: authors list (link)
• Oláh J, Tokési N, Vincze O; et al. (2006). "Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies". FEBS Lett. 580 (25): 5807–14. doi:10.1016/j.febslet.2006.09.037. PMID 17027006.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vincze O, Tökési N, Oláh J; et al. (2007). "Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions". Biochemistry. 45 (46): 13818–26. doi:10.1021/bi061305e. PMID 17105200.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hlavanda E, Klement E, Kókai E; et al. (2007). "Phosphorylation blocks the activity of tubulin polymerization-promoting protein (TPPP): identification of sites targeted by different kinases". J. Biol. Chem. 282 (40): 29531–9. doi:10.1074/jbc.M703466200. PMID 17693641.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Song YJ, Lundvig DM, Huang Y; et al. (2007). "p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy". Am. J. Pathol. 171 (4): 1291–303. doi:10.2353/ajpath.2007.070201. PMID 17823288.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)