HINT1

Histidine triad nucleotide binding protein 1
PDB rendering based on 1av5.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1av5​, 1kpa​, 1kpb​, 1kpc​, 1kpe​, 1kpf​, 1rzy​, 3rhn​, 4rhn​, 5rhn​, 6rhn​
Identifiers
Symbols	HINT1 ; HINT; PKCI-1; PRKCNH1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3904
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Histidine triad nucleotide binding protein 1, also known as HINT1, is a human gene.

Further reading

• Brzoska PM, Chen H, Zhu Y; et al. (1995). "The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor". Proc. Natl. Acad. Sci. U.S.A. 92 (17): 7824–8. PMID 7644499.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lima CD, Klein MG, Weinstein IB, Hendrickson WA (1996). "Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins". Proc. Natl. Acad. Sci. U.S.A. 93 (11): 5357–62. PMID 8643579.CS1 maint: Multiple names: authors list (link)
• Brzoska PM, Chen H, Levin NA; et al. (1997). "Cloning, mapping, and in vivo localization of a human member of the PKCI-1 protein family (PRKCNH1)". Genomics. 36 (1): 151–6. doi:10.1006/geno.1996.0435. PMID 8812426.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lima CD, Klein MG, Hendrickson WA (1997). "Structure-based analysis of catalysis and substrate definition in the HIT protein family". Science. 278 (5336): 286–90. PMID 9323207.CS1 maint: Multiple names: authors list (link)
• Klein MG, Yao Y, Slosberg ED; et al. (1998). "Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family". Exp. Cell Res. 244 (1): 26–32. doi:10.1006/excr.1998.4153. PMID 9770345.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weitzdoerfer R, Stolzlechner D, Dierssen M; et al. (2002). "Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain". J. Neural Transm. Suppl. (61): 347–59. PMID 11771757.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bieganowski P, Garrison PN, Hodawadekar SC; et al. (2002). "Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3". J. Biol. Chem. 277 (13): 10852–60. doi:10.1074/jbc.M111480200. PMID 11805111.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brenner C (2002). "Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases". Biochemistry. 41 (29): 9003–14. PMID 12119013.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gevaert K, Goethals M, Martens L; et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Galey D, Becker K, Haughey N; et al. (2003). "Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes". J. Neurovirol. 9 (3): 358–71. PMID 12775419.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weiske J, Huber O (2006). "The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activity". J. Biol. Chem. 281 (37): 27356–66. doi:10.1074/jbc.M513452200. PMID 16835243.
• Ajit SK, Ramineni S, Edris W; et al. (2007). "RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling". Cell. Signal. 19 (4): 723–30. doi:10.1016/j.cellsig.2006.09.008. PMID 17126529.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)