POLK

Polymerase (DNA directed) kappa
File:PBB Protein POLK image.jpg PDB rendering based on 1t94.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1t94​, 2oh2​
Identifiers
Symbols	POLK ; POLQ; DINB1; DINP
External IDs	Template:OMIM5 Template:MGI HomoloGene: 32140
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Polymerase (DNA directed) kappa, also known as POLK, is a human gene.

Further reading

• Bavoux C, Hoffmann JS, Cazaux C (2005). "Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa". Biochimie. 87 (7): 637–46. doi:10.1016/j.biochi.2005.02.007. PMID 15989980.CS1 maint: Multiple names: authors list (link)
• Gerlach VL, Aravind L, Gotway G; et al. (1999). "Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily". Proc. Natl. Acad. Sci. U.S.A. 96 (21): 11922–7. PMID 10518552.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ogi T, Kato T, Kato T, Ohmori H (2000). "Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB". Genes Cells. 4 (11): 607–18. PMID 10620008.CS1 maint: Multiple names: authors list (link)
• Johnson RE, Prakash S, Prakash L (2000). "The human DINB1 gene encodes the DNA polymerase Poltheta". Proc. Natl. Acad. Sci. U.S.A. 97 (8): 3838–43. PMID 10760255.CS1 maint: Multiple names: authors list (link)
• Ohashi E, Ogi T, Kusumoto R; et al. (2000). "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa". Genes Dev. 14 (13): 1589–94. PMID 10887153.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerlach VL, Feaver WJ, Fischhaber PL, Friedberg EC (2001). "Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene". J. Biol. Chem. 276 (1): 92–8. doi:10.1074/jbc.M004413200. PMID 11024016.CS1 maint: Multiple names: authors list (link)
• Haracska L, Unk I, Johnson RE; et al. (2002). "Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA". Mol. Cell. Biol. 22 (3): 784–91. PMID 11784855.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Washington MT, Johnson RE, Prakash L, Prakash S (2002). "Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini". Proc. Natl. Acad. Sci. U.S.A. 99 (4): 1910–4. doi:10.1073/pnas.032594399. PMID 11842189.CS1 maint: Multiple names: authors list (link)
• Suzuki N, Ohashi E, Kolbanovskiy A; et al. (2002). "Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)". Biochemistry. 41 (19): 6100–6. PMID 11994005.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fischhaber PL, Gerlach VL, Feaver WJ; et al. (2002). "Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides". J. Biol. Chem. 277 (40): 37604–11. doi:10.1074/jbc.M206027200. PMID 12145297.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bergoglio V, Bavoux C, Verbiest V; et al. (2003). "Localisation of human DNA polymerase kappa to replication foci". J. Cell. Sci. 115 (Pt 23): 4413–8. PMID 12414988.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Haracska L, Prakash L, Prakash S (2003). "Role of human DNA polymerase kappa as an extender in translesion synthesis". Proc. Natl. Acad. Sci. U.S.A. 99 (25): 16000–5. doi:10.1073/pnas.252524999. PMID 12444249.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wolfle WT, Washington MT, Prakash L, Prakash S (2003). "Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions". Genes Dev. 17 (17): 2191–9. doi:10.1101/gad.1108603. PMID 12952891.CS1 maint: Multiple names: authors list (link)
• Haracska L, Prakash L, Prakash S (2003). "A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair". Genes Dev. 17 (22): 2777–85. doi:10.1101/gad.1146103. PMID 14630940.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Suzuki N, Itoh S, Poon K; et al. (2004). "Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases eta and kappa". Biochemistry. 43 (20): 6304–11. doi:10.1021/bi0360298. PMID 15147214.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ohashi E, Murakumo Y, Kanjo N; et al. (2005). "Interaction of hREV1 with three human Y-family DNA polymerases". Genes Cells. 9 (6): 523–31. doi:10.1111/j.1356-9597.2004.00747.x. PMID 15189446.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Washington MT, Minko IG, Johnson RE; et al. (2004). "Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa". Mol. Cell. Biol. 24 (13): 5687–93. doi:10.1128/MCB.24.13.5687-5693.2004. PMID 15199127.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Uljon SN, Johnson RE, Edwards TA; et al. (2005). "Crystal structure of the catalytic core of human DNA polymerase kappa". Structure. 12 (8): 1395–404. doi:10.1016/j.str.2004.05.011. PMID 15296733.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)