GOPC

Golgi associated PDZ and coiled-coil motif containing
PDB rendering based on 2dc2.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2dc2​
Identifiers
Symbols	GOPC ; FIG; CAL; GOPC1; PIST; dJ94G16.2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 10695
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Golgi associated PDZ and coiled-coil motif containing, also known as GOPC, is a human gene.

PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM]

Further reading

• Loo MA, Jensen TJ, Cui L; et al. (1999). "Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome". EMBO J. 17 (23): 6879–87. doi:10.1093/emboj/17.23.6879. PMID 9843494.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Neudauer CL, Joberty G, Macara IG (2001). "PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10". Biochem. Biophys. Res. Commun. 280 (2): 541–7. doi:10.1006/bbrc.2000.4160. PMID 11162552.CS1 maint: Multiple names: authors list (link)
• Charest A, Lane K, McMahon K, Housman DE (2001). "Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6". J. Biol. Chem. 276 (31): 29456–65. doi:10.1074/jbc.M104137200. PMID 11384996.CS1 maint: Multiple names: authors list (link)
• Yao R, Maeda T, Takada S, Noda T (2001). "Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled". Biochem. Biophys. Res. Commun. 286 (4): 771–8. doi:10.1006/bbrc.2001.5430. PMID 11520064.CS1 maint: Multiple names: authors list (link)
• Cheng J, Moyer BD, Milewski M; et al. (2002). "A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression". J. Biol. Chem. 277 (5): 3520–9. doi:10.1074/jbc.M110177200. PMID 11707463.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yao R, Ito C, Natsume Y; et al. (2002). "Lack of acrosome formation in mice lacking a Golgi protein, GOPC". Proc. Natl. Acad. Sci. U.S.A. 99 (17): 11211–6. doi:10.1073/pnas.162027899. PMID 12149515.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yue Z, Horton A, Bravin M; et al. (2002). "A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice". Neuron. 35 (5): 921–33. PMID 12372286.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gentzsch M, Cui L, Mengos A; et al. (2003). "The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins". J. Biol. Chem. 278 (8): 6440–9. doi:10.1074/jbc.M211050200. PMID 12471024.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Charest A, Kheifets V, Park J; et al. (2003). "Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma". Proc. Natl. Acad. Sci. U.S.A. 100 (3): 916–21. doi:10.1073/pnas.242741799. PMID 12538861.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Charest A, Lane K, McMahon K; et al. (2003). "Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)". Genes Chromosomes Cancer. 37 (1): 58–71. doi:10.1002/gcc.10207. PMID 12661006.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hassel B, Schreff M, Stube EM; et al. (2003). "CALEB/NGC interacts with the Golgi-associated protein PIST". J. Biol. Chem. 278 (41): 40136–43. doi:10.1074/jbc.M305577200. PMID 12885772.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cheng J, Wang H, Guggino WB (2004). "Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL". J. Biol. Chem. 279 (3): 1892–8. doi:10.1074/jbc.M308640200. PMID 14570915.CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brill LM, Salomon AR, Ficarro SB; et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hruska-Hageman AM, Benson CJ, Leonard AS; et al. (2004). "PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current". J. Biol. Chem. 279 (45): 46962–8. doi:10.1074/jbc.M405874200. PMID 15317815.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• He J, Bellini M, Xu J; et al. (2005). "Interaction with cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) inhibits beta1-adrenergic receptor surface expression". J. Biol. Chem. 279 (48): 50190–6. doi:10.1074/jbc.M404876200. PMID 15358775.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cheng J, Wang H, Guggino WB (2005). "Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10". J. Biol. Chem. 280 (5): 3731–9. doi:10.1074/jbc.M410026200. PMID 15546864.CS1 maint: Multiple names: authors list (link)
• Hicks SW, Machamer CE (2005). "Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST". J. Biol. Chem. 280 (32): 28944–51. doi:10.1074/jbc.M504937200. PMID 15951434.