RIPK1

Receptor (TNFRSF)-interacting serine-threonine kinase 1
Identifiers
Symbols	RIPK1 ; RIP; FLJ39204
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2820
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RIPK1 209941 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Receptor (TNFRSF)-interacting serine-threonine kinase 1, also known as RIPK1, is a human gene.

Further reading

• Festjens N, Vanden Berghe T, Cornelis S, Vandenabeele P (2007). "RIP1, a kinase on the crossroads of a cell's decision to live or die". Cell Death Differ. 14 (3): 400–10. doi:10.1038/sj.cdd.4402085. PMID 17301840.CS1 maint: Multiple names: authors list (link)
• Stanger BZ, Leder P, Lee TH; et al. (1995). "RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death". Cell. 81 (4): 513–23. PMID 7538908.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hsu H, Huang J, Shu HB; et al. (1996). "TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex". Immunity. 4 (4): 387–96. PMID 8612133.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takeuchi M, Rothe M, Goeddel DV (1996). "Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins". J. Biol. Chem. 271 (33): 19935–42. PMID 8702708.CS1 maint: Multiple names: authors list (link)
• Duan H, Dixit VM (1997). "RAIDD is a new 'death' adaptor molecule". Nature. 385 (6611): 86–9. doi:10.1038/385086a0. PMID 8985253.
• Ahmad M, Srinivasula SM, Wang L; et al. (1997). "CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP". Cancer Res. 57 (4): 615–9. PMID 9044836.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chaudhary PM, Eby M, Jasmin A; et al. (1998). "Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway". Immunity. 7 (6): 821–30. PMID 9430227.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Juo P, Kuo CJ, Yuan J, Blenis J (1998). "Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade". Curr. Biol. 8 (18): 1001–8. PMID 9740801.CS1 maint: Multiple names: authors list (link)
• Li Y, Kang J, Friedman J; et al. (1999). "Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis". Proc. Natl. Acad. Sci. U.S.A. 96 (3): 1042–7. PMID 9927690.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu PW, Huang BC, Shen M; et al. (1999). "Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB". Curr. Biol. 9 (10): 539–42. PMID 10339433.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sanz L, Sanchez P, Lallena MJ; et al. (1999). "The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation". EMBO J. 18 (11): 3044–53. doi:10.1093/emboj/18.11.3044. PMID 10356400.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sun X, Lee J, Navas T; et al. (1999). "RIP3, a novel apoptosis-inducing kinase". J. Biol. Chem. 274 (24): 16871–5. PMID 10358032.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Izumi KM, Cahir McFarland ED, Ting AT; et al. (1999). "The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation". Mol. Cell. Biol. 19 (8): 5759–67. PMID 10409763.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lin Y, Devin A, Rodriguez Y, Liu ZG (1999). "Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis". Genes Dev. 13 (19): 2514–26. PMID 10521396.CS1 maint: Multiple names: authors list (link)
• Chaudhary PM, Jasmin A, Eby MT, Hood L (1999). "Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins". Oncogene. 18 (42): 5738–46. doi:10.1038/sj.onc.1202976. PMID 10523854.CS1 maint: Multiple names: authors list (link)
• Lewis J, Devin A, Miller A; et al. (2000). "Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation". J. Biol. Chem. 275 (14): 10519–26. PMID 10744744.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kataoka T, Budd RC, Holler N; et al. (2000). "The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways". Curr. Biol. 10 (11): 640–8. PMID 10837247.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Inohara N, Koseki T, Lin J; et al. (2000). "An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways". J. Biol. Chem. 275 (36): 27823–31. doi:10.1074/jbc.M003415200. PMID 10880512.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chaudhary PM, Eby MT, Jasmin A; et al. (2000). "Activation of the NF-kappaB pathway by caspase 8 and its homologs". Oncogene. 19 (39): 4451–60. doi:10.1038/sj.onc.1203812. PMID 11002417.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim JW, Choi EJ, Joe CO (2000). "Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP". Oncogene. 19 (39): 4491–9. doi:10.1038/sj.onc.1203796. PMID 11002422.CS1 maint: Multiple names: authors list (link)