KIF4A

Kinesin family member 4A
Identifiers
Symbols	KIF4A ; FLJ12530; FLJ12655; FLJ14204; FLJ20631; HSA271784; KIF4; KIF4-G1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 69022
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE KIF4A 218355 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Kinesin family member 4A, also known as KIF4A, is a human gene.

Kinesins, such as KIF4A, are microtubule-based motor proteins that generate directional movement along microtubules. They are involved in many crucial cellular processes, including cell division (Zhu and Jiang, 2005).[supplied by OMIM]

Further reading

• Sekine Y, Okada Y, Noda Y; et al. (1994). "A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally". J. Cell Biol. 127 (1): 187–201. PMID 7929562.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yan RT, Wang SZ (1997). "Increased chromokinesin immunoreactivity in retinoblastoma cells". Gene. 189 (2): 263–7. PMID 9168136.
• Tang Y, Winkler U, Freed EO; et al. (1999). "Cellular motor protein KIF-4 associates with retroviral Gag". J. Virol. 73 (12): 10508–13. PMID 10559369.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ha MJ, Yoon J, Moon E; et al. (2000). "Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization". Cytogenet. Cell Genet. 88 (1–2): 41–2. PMID 10773663.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Oh S, Hahn H, Torrey TA; et al. (2000). "Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein". Biochim. Biophys. Acta. 1493 (1–2): 219–24. PMID 10978527.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee YM, Lee S, Lee E; et al. (2002). "Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during mitosis". Biochem. J. 360 (Pt 3): 549–56. PMID 11736643.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee YM, Kim W (2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". Biochem. J. 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMID 12809554.
• Leonard D, Ajuh P, Lamond AI, Legerski RJ (2003). "hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing". Biochem. Biophys. Res. Commun. 308 (4): 793–801. PMID 12927788.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee YM, Kim W (2004). "Kinesin superfamily protein member 4 (KIF4) is localized to midzone and midbody in dividing cells". Exp. Mol. Med. 36 (1): 93–7. PMID 15031677.
• Geiman TM, Sankpal UT, Robertson AK; et al. (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMID 15148359.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kurasawa Y, Earnshaw WC, Mochizuki Y; et al. (2005). "Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation". EMBO J. 23 (16): 3237–48. doi:10.1038/sj.emboj.7600347. PMID 15297875.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mazumdar M, Sundareshan S, Misteli T (2004). "Human chromokinesin KIF4A functions in chromosome condensation and segregation". J. Cell Biol. 166 (5): 613–20. doi:10.1083/jcb.200401142. PMID 15326200.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhu C, Jiang W (2005). "Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis". Proc. Natl. Acad. Sci. U.S.A. 102 (2): 343–8. doi:10.1073/pnas.0408438102. PMID 15625105.
• Ross MT, Grafham DV, Coffey AJ; et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nousiainen M, Silljé HH, Sauer G; et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)