Non-alcoholic fatty liver disease causes
Non-Alcoholic Fatty Liver Disease Microchapters |
Differentiating Non-Alcoholic Fatty Liver Disease from other Diseases |
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Non-alcoholic fatty liver disease causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
There are no clear causes of NAFLD, although various disorders are strongly associated with it including obesity, diabetes mellitus type 2, and dyslipidemia, all of which are components of the metabolic syndrome. Other less common causes of non-alcoholic fatty liver disease include oxidative stress, hormonal imbalances, endotoxemia and mitochondrial abnormalities.
Causes
- Common causes in the development of NAFLD is related to conditions associated with obesity such as insulin resistance and metabolic syndrome.[1][2]It is estimated that approximately 80% of the obese people suffer from NAFLD.[3]
- Patients who are having type 2 diabetes mellitus are more prone to develop Nafld[4][5]
- Less commonly patients with hypertension and dyslipidemia are also associated with developing NAFLD
Secondary causes
- NAFLD can also be caused by the following medications (termed secondary NAFLD):
- Amiodarone
- Antiviral drugs (nucleoside analogues)
- Aspirin / NSAIDS
- Corticosteroids
- Methotrexate
- Nifedipine
- Perhexiline
- Tamoxifen
- Tetracycline
- Valproic acid
- Viral Hepatitis.
- Rapid weight loss.
- Malnutrition.
- High levels of triglyceride in blood.
- Sleep apnea.
- Hypothyroidism
- Hypopituitarism .
References
- ↑ "Nonalcoholic Fatty Liver Disease".
- ↑ Sung KC, Jeong WS, Wild SH, Byrne CD (2012). "Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes". Diabetes Care. 35 (4): 717–22. doi:10.2337/dc11-1853. PMC 3308286. PMID 22338098.
- ↑ "Nonalcoholic fatty liver disease".
- ↑ "Nonalcoholic Fatty Liver Disease".
- ↑ "Nonalcoholic Fatty Liver Disease & NASH | NIDDK".
Non-Alcoholic Fatty Liver Disease Microchapters |
Differentiating Non-Alcoholic Fatty Liver Disease from other Diseases |
---|
Diagnosis |
Treatment |
Case studies |
Non-alcoholic fatty liver disease causes On the Web |
American Roentgen Ray Society Images of Non-alcoholic fatty liver disease causes |
Directions to Hospitals Treating Non-alcoholic fatty liver disease |
Risk calculators and risk factors for Non-alcoholic fatty liver disease causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief:
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