Non-alcoholic fatty liver disease history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

The majority of patients with non-alcoholic fatty liver disease are asymptomatic. However, infrequently patients may complain of fatigue, malaise and dull right upper quadrant abdominal discomfort. Mild jaundice can rarely be noticed. More commonly it is diagnosed as a result of abnormal liver function tests during routine blood tests. Often following an asymptomatic course, the disease may present first with cirrhosis and/or the complication of portal hypertension.

History

There is no significant history to be noted in patients with non-alcoholic fatty liver disease. However, history of alcohol consumption and family history of non-alcoholic fatty liver disease must be obtained.

Symptoms

Usually, NAFLD [Nonalcoholic fatty liver disease] presents with no or few symptoms and sighs but when it does it shows the following

• Hepatomegaly
• Patient presents with fatigue
• Abdominal swelling (ascites)
• Enlarged breasts in men- Gynecomastia ( due to decreased estrogen clearance by liver damage )
• Pain in the upper right abdomen
• Yellowing of the skin and eyes (jaundice)
• Splenomegaly
• The disease may present first with cirrhosis and/or the complication of portal hypertension.