American Pancreatic Association practice guidelines for chronic pancreatitis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]

American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: Evidence-Based Report on Diagnostic Guidelines[1]

Epidemiology and Risk Factors

Recommendation Evidence Level Strength of Recommendation
Data on population-based estimates of CP are emerging. Low Conditional
A small fraction of patients progress from AP to CP. Moderate Conditional
Alcohol and smoking are independent risk factors for CP. Both are associated with disease progression, and their risks are likely multiplicative. High Strong
The spectrum of risk factors for CP has broadened. Low Conditional
Genetic discoveries are rapidly uncovering new susceptibility factors. Knowledge of gene and gene-environment interactions may translate into new diagnostic and treatment paradigms. Moderate Strong

References

  1. Conwell DL, Lee LS, Yadav D, Longnecker DS, Miller FH, Mortele KJ, Levy MJ, Kwon R, Lieb JG, Stevens T, Toskes PP, Gardner TB, Gelrud A, Wu BU, Forsmark CE, Vege SS (2014). "American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines". Pancreas. 43 (8): 1143–62. doi:10.1097/MPA.0000000000000237. PMC 5434978. PMID 25333398.

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