Neonatal jaundice laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

OR

[Test] is usually normal among patients with [disease name].

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

• An elevated concentration of serum bilirubin is diagnostic of neonatal jaundice.
• Laboratory findings consistent with the diagnosis of neonatal jaudice include:
  • Increase of the total bilirubin level more than 5 mg/dl.
  • Increase of the conjugated bilirubin level more than 2 mg/dl.

• Transcutaneous bilirubin level measurment can be diagnostic in cases of mild jaundice.
• Other laboratory tests recommended in cases of neonatal jaundice include the following:
  • Blood type and Rh determination in mother and infant
  • Direct Coombs test
  • Hemoglobin and hematocrit values
  • Serum albumin level
  • Liver function tests
  • Peripheral blood film for erythrocyte morphology
  • Reticulocyte count
  • Tests for viral and/or parasitic infection