Neonatal jaundice medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
The mainstay of treatment of patients with neonatal jaundice is phototherapy and blood exchange.
Medical Therapy
Infants with neonatal jaundice are often treated with bili lights, exposing them to high levels of colored light to break down the bilirubin. This works due to a photo oxidation process occurring on the bilirubin in the subcutaneous tissues of the neonate. Light energy creates isomerization of the bilirubin and consequently transformation into compounds that the new born can excrete via urine and stools. Blue light is typically used for this purpose.
The bilirubin levels for initiative of phototherapy varies depends on the age and health status of the newborn. However any newborn with a total serum bilirubin greater than 359 umol/l ( 21 mg/dL ) should receive phototherapy.[1]
Phototherapy
References
- ↑ American Academy of Pediatrics Subcommittee on Hyperbilirubinemia (2004). "Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation". Pediatrics. 114 (1): 297–316. doi:10.1542/peds.114.1.297. PMID 15231951. Unknown parameter
|month=ignored (help) - ↑ Dobbs, R H (1975-11). "Phototherapy". Archives of Disease in Childhood. 50 (11): 833–836. doi:10.1136/adc.50.11.833. ISSN 0003-9888. PMC 1545706. PMID 1108807. Unknown parameter
|coauthors=ignored (help); Check date values in:|date=(help) - ↑ Cremer, R. J. (1958-05-24). "INFLUENCE OF LIGHT ON THE HYPERBILIRUBINÆMIA OF INFANTS". The Lancet. 271 (7030): 1094–1097. doi:10.1016/S0140-6736(58)91849-X. ISSN 0140-6736. Retrieved 2010-08-01. Unknown parameter
|coauthors=ignored (help) - ↑ Amato M, Inaebnit D (1991). "Clinical usefulness of high intensity green light phototherapy in the treatment of neonatal jaundice". Eur. J. Pediatr. 150 (4): 274–6. doi:10.1007/BF01955530. PMID 2029920. Unknown parameter
|month=ignored (help) - ↑ Leung C, Soong WJ, Chen SJ (1992). "[Effect of light on total micro-bilirubin values in vitro]". Zhonghua Yi Xue Za Zhi (Taipei) (in Chinese). 50 (1): 41–5. PMID 1326385. Unknown parameter
|month=ignored (help) - ↑ Stokowski LA (2006). "Fundamentals of phototherapy for neonatal jaundice". Adv Neonatal Care. 6 (6): 303–12. doi:10.1016/j.adnc.2006.08.004. PMID 17208161. Unknown parameter
|month=ignored (help) - ↑ Ennever JF, Sobel M, McDonagh AF, Speck WT (1984). "Phototherapy for neonatal jaundice: in vitro comparison of light sources". Pediatr. Res. 18 (7): 667–70. doi:10.1203/00006450-198407000-00021. PMID 6540860. Unknown parameter
|month=ignored (help)