Gastroparesis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]

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Complications

Primary complications of gastroparesis include:

• Fluctuations in blood glucose due to unpredictable digestion times (in diabetic patients)
• General malnutrition due to the symptoms of the disease (which frequently include vomiting and reduced appetite) as well as the dietary changes necessary to manage it
• Severe fatigue and weight loss due to calorie deficit
• Intestinal obstruction due to the formation of bezoars (solid masses of undigested food)
• Bacterial infection due to overgrowth in undigested food
• Dehydration
• Electrolyte imbalances

Prognosis

Many treatments seem to provide only temporary benefit.