Barrett's esophagus epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]
Overview
Barrett's esophagus can be seen in younger patients, but is most commonly diagnosed in patients ~ 55 years old.
Epidemiology and Demographics
- Barrett's esophagus can be seen in younger patients, but is most commonly diagnosed in patients ~ 55 years old.[1][2]
- This can be seen on EGD (esophago-gastroduodenoscopy) in ~ 1 % of all patients, but in up to 20 % of those with symptoms of GERD (Gastroesophageal Reflux Disease). Although the diagnosis can be presumed during the EGD, it needs to be confirmed by biopsy.
- It is more common in caucasians, than blacks or Asians. The prevalence in hispanic population is unclear, some studies compare it to caucasian prevalence and other studies show a lower prevalence.[3][4]
- It is an acquired condition, seen in children but rarely in younger than age of five.[2]
- More common in male, with a male to female ratio of 1.96:1.[5][6]
Incidence
- The incidence of Barrett's esophagus is approximately 400 per 100,000 individuals worldwide.[7]
Prevalence
- The prevalence of barrett's esophagus is approximately 2000 per 100,000 individuals worldwide.[8]
Age
- The incidence of Barrett's esophagus increases with age; the median age at diagnosis is 55 years.[1]
- Barrett's esophagus hardly affects individuals younger than 5 years of age.[2]
Race
- Barrett's esophagus usually affects individuals of the Caucasians race. Blacks and Asians individuals are less likely to develop Barrett's esophagus.
- The prevalence in hispanic population is unclear, some studies compare it to caucasian prevalence and other studies show a lower prevalence.[3][4]
Gender
- Men are more commonly affected by Barrett's esophagus than female.[6][9] The men to female ratio is approximately 1.96 to 1.[5]
Region
- Barrett's esophagus is a common disease that tends to affect equally to people in both Asian countries as well as Western countries.[10]
Developed Countries
- In one of the study in Sweden, it is published that the estimated rate of Barrett's esophagus in the general population was around 1.6 percent.[11]
- Based on these data, the estimated prevalence rate of Barrett's esophagus in the United States population, it would be around 3.3 million individuals.[12]
Developing Countries
- Barrett's esophagus is very common in developing countries and it shares the same kind of risk factors and potential towards neoplastic process as compared to those seen in developed countries.[10]
References
- ↑ 1.0 1.1 Spechler SJ (1996). "Barrett's esophagus". Semin. Gastrointest. Dis. 7 (2): 51–60. PMID 8705259. Unknown parameter
|month=ignored (help) - ↑ 2.0 2.1 2.2 Hassall E (1997). "Columnar-lined esophagus in children". Gastroenterol Clin North Am. 26 (3): 533–48. PMID 9309403.
- ↑ 3.0 3.1 Corley DA, Kubo A, Levin TR; et al. (2009). "Race, ethnicity, sex and temporal differences in Barrett's oesophagus diagnosis: a large community-based study, 1994-2006". Gut. 58 (2): 182–8. doi:10.1136/gut.2008.163360. PMC 2671084. PMID 18978173. Unknown parameter
|month=ignored (help) - ↑ 4.0 4.1 Bersentes K, Fass R, Padda S, Johnson C, Sampliner RE (1998). "Prevalence of Barrett's esophagus in Hispanics is similar to Caucasians". Dig. Dis. Sci. 43 (5): 1038–41. PMID 9590419. Unknown parameter
|month=ignored (help) - ↑ 5.0 5.1 Cook MB, Wild CP, Forman D (2005). "A systematic review and meta-analysis of the sex ratio for Barrett's esophagus, erosive reflux disease, and nonerosive reflux disease". Am. J. Epidemiol. 162 (11): 1050–61. doi:10.1093/aje/kwi325. PMID 16221http://wikidoc.org/index.php?title=Barrett%27s_esophagus_epidemiology_and_demographics&action=edit§ion=2805 Check
|pmid=value (help). Unknown parameter|month=ignored (help) - ↑ 6.0 6.1 Ek WE, Lagergren K, Cook M, Wu AH, Abnet CC, Levine D; et al. (2016). "Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma". Int J Cancer. 138 (5): 1146–52. doi:10.1002/ijc.29863. PMC 4715576. PMID 26414697.
- ↑ Verhaegen J, Glupczynski Y, Verbist L, Blogie M, Vandeven J, Yourassowsky E; et al. (1990). "Capsular types and antibiotic sensitivity of pneumococci isolated from patients with serious infections in Belgium 1980 to 1988". Eur J Clin Microbiol Infect Dis. 9 (6): 390–5. PMID 2387291.
- ↑ Whiteman DC, Kendall BJ (2016). "Barrett's oesophagus: epidemiology, diagnosis and clinical management". Med J Aust. 205 (7): 317–24. PMID 27681974.
- ↑ Ward EM, Wolfsen HC, Achem SR, Loeb DS, Krishna M, Hemminger LL; et al. (2006). "Barrett's esophagus is common in older men and women undergoing screening colonoscopy regardless of reflux symptoms". Am J Gastroenterol. 101 (1): 12–7. doi:10.1111/j.1572-0241.2006.00379.x. PMID 16405528.
- ↑ 10.0 10.1 Shiota S, Singh S, Anshasi A, El-Serag HB (2015). "Prevalence of Barrett's Esophagus in Asian Countries: A Systematic Review and Meta-analysis". Clin Gastroenterol Hepatol. 13 (11): 1907–18. doi:10.1016/j.cgh.2015.07.050. PMC 4615528. PMID 26260107.
- ↑ Ronkainen J, Aro P, Storskrubb T, Johansson SE, Lind T, Bolling-Sternevald E; et al. (2005). "Prevalence of Barrett's esophagus in the general population: an endoscopic study". Gastroenterology. 129 (6): 1825–31. doi:10.1053/j.gastro.2005.08.053. PMID 16344051.
- ↑ Sampliner RE (2005). "A population prevalence of Barrett's esophagus--finally". Gastroenterology. 129 (6): 2101–3. doi:10.1053/j.gastro.2005.10.029. PMID 16344076.