Gastroparesis Diagnostic Study of Choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]; Madhu Sigdel M.B.B.S.[3]

Overview

Gastric emptying scintigraphy is considered a gold standard diagnostic test for gastroparesis. Delayed gastric emptying is confirmed by 10% gastric retention at 4 hours. Factors that affect the results of this test include medications, tobacco smoking, and hyperglycemia.

Gastric emptying scintigraphy is considered a gold standard diagnostic test for gastroparesis.^[1]^[2]^[3]^[4]
The method for this test is eating a low-fat, egg-white meal followed by repeated scans to measure the rate of gastric emptying at 0, 1, 2, and 4 hours.
The delayed gastric emptying would be confirmed, if there is:
- Gastric retention of 90% at 1 hour
- Gastric retention of 60% at 2 hours (greater accuracy for detecting accelerated gastric emptying)
- Gastric retention of 10% at 4 hours (higher accuracy for detecting slow gastric emptying)
Factors that might affect on the results of gastric emptying studies include:
- Medications that slow down gastric emptying:
- Tobacco smoking
- Hyperglycemia
The advantages of gastric emptying scintigraphy include:
- Noninvasive
- Quantitative
- High sensitivity
- High specificity

↑ Tang, Derek M.; Friedenberg, Frank K. (2011). "Gastroparesis: Approach, Diagnostic Evaluation, and Management". Disease-a-Month. 57 (2): 74–101. doi:10.1016/j.disamonth.2010.12.007. ISSN 0011-5029.
↑ Koch, Kenneth L.; Calles-Escandón, Jorge (2015). "Diabetic Gastroparesis". Gastroenterology Clinics of North America. 44 (1): 39–57. doi:10.1016/j.gtc.2014.11.005. ISSN 0889-8553.
↑ Abell TL, Camilleri M, Donohoe K, Hasler WL, Lin HC, Maurer AH; et al. (2008). "Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine". Am J Gastroenterol. 103 (3): 753–63. doi:10.1111/j.1572-0241.2007.01636.x. PMID 18028513.
↑ Waseem S, Moshiree B, Draganov PV (2009). "Gastroparesis: current diagnostic challenges and management considerations". World J Gastroenterol. 15 (1): 25–37. PMC 2653292. PMID 19115465.