Cystic fibrosis CT
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American Roentgen Ray Society Images of Cystic fibrosis CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
CT scan
Computed tomography (CT scan) findings in patients with cystic fibrosis are more sensitive as compared to the pulmonary function tests. It has a crucial role in the assessment of pulmonary damage over time, detecting complications and monitoring treatment.[1]
Chest
- Mosaic attenuation (localized hyperinflation due to small airway obstruction) on expiratory chest computed tomography (CT) is common in early life cystic fibrosis and often referred to as "air trapping".[2]
- Chest Ct scan in patients with cystic fibrosis can identify a wide range of morphological abnormalities include:[1]
- Bronchiectasis(which is progressive, irreversible and probably the most relevant structural change in cystic fibrosis)
- Peribronchial thickening
- Mucous plugging
- sacculations
- Abscesses,
- bullae,
- emphysema,
- air trapping,
- hyperinflation,
- collapse,
- consolidation,
- mosaic perfusion,
- ground-glass opacities,
- acinar nodules,
- alveolar consolidation
- thickening of interlobular and intralobular septa
Abdomen
CT scan of abdomen in patients with cystic fibrosis may include these findings:[3][4]
- Diffuse and complete fatty replacement of pancreas is the most common imaging appearance.
- Fibrosis of the pancreas can be detectable on CT scan.
- Intestinal findings on CT may include obstruction (more common in children).
Images
CT demonstrates mucous plugging and complete pancreatic atrophy[5]
References
- ↑ 1.0 1.1 Rybacka A, Karmelita-Katulska K (2016). "The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis". Pol J Radiol. 81: 141–5. doi:10.12659/PJR.896051. PMC 4821342. PMID 27103945.
- ↑ Rosenow T, Ramsey K, Turkovic L, Murray CP, Mok LC, Hall GL, Stick SM (September 2017). "Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?". Pediatr. Pulmonol. 52 (9): 1150–1156. doi:10.1002/ppul.23754. PMID 28682006.
- ↑ Carucci LR, Jacobs JE (2003). "Focal fatty sparing of the pancreatic head in cystic fibrosis: CT findings". Abdom Imaging. 28 (6): 853–5. PMID 14753605.
- ↑ Lugo-Olivieri CH, Soyer PA, Fishman EK (1998). "Cystic fibrosis: spectrum of thoracic and abdominal CT findings in the adult patient". Clin Imaging. 22 (5): 346–54. PMID 9755398.
- ↑ "Cystic fibrosis | Radiology Case | Radiopaedia.org".