Rheumatoid arthritis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Causes
Causes
The cause of rheumatoid arthritis is idiopathic but genetic, environmental, hormonal, immunologic, infectious factors, socioeconomic, psychological, and lifestyle factors play important role in the development of rheumatoid arthritis.
- Genetic factors:[1]
- In United States, HLA-DR4 cluster(HLA-DR beta *0401, 0404, or 0405,) part of one of the peptide-binding sites of certain HLA-DR molecules associated with rheumatoid arthritis.
- In European countries, HLA-DR1 (HLA-DR beta *0101) is associated with rheumatoid arthritis.
- Infectious agents: Various infectious agents involved in rheumatoid arthritis are:[2][3]
- Mycoplasma
- Epstein-Barr virus (EBV)
- Rubella virus
- Porphyromonas gingivalis
Less Common Causes
Less common causes of disease name include:
- [Cause1]
- [Cause2]
- [Cause3]
Genetic Causes
- [Disease name] is caused by a mutation in the [gene name] gene.
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
List the causes of the disease in alphabetical order.
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3References
- ↑ Barton A, Worthington J (October 2009). "Genetic susceptibility to rheumatoid arthritis: an emerging picture". Arthritis Rheum. 61 (10): 1441–6. doi:10.1002/art.24672. PMID 19790122.
- ↑ Hitchon CA, Chandad F, Ferucci ED, Willemze A, Ioan-Facsinay A, van der Woude D, Markland J, Robinson D, Elias B, Newkirk M, Toes RM, Huizinga TW, El-Gabalawy HS (June 2010). "Antibodies to porphyromonas gingivalis are associated with anticitrullinated protein antibodies in patients with rheumatoid arthritis and their relatives". J. Rheumatol. 37 (6): 1105–12. doi:10.3899/jrheum.091323. PMID 20436074.
- ↑ Routsias JG, Goules JD, Goules A, Charalampakis G, Pikazis D (July 2011). "Autopathogenic correlation of periodontitis and rheumatoid arthritis". Rheumatology (Oxford). 50 (7): 1189–93. doi:10.1093/rheumatology/ker090. PMID 21343168.