Scleroderma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
Epidemiology and Demographics
Incidence
- The incidence of scleroderma is approximately 0.23 to 2.28 cases per 100,000 individuals worldwide.[1]
- The incidence of scleroderma is approximately 2 per 100,000 individuals in the United States.[2]
Prevalence
- The prevalence of scleroderma is approximately 5 to 30 cases per 100,000 individuals worldwide.[1]
- In 1990, the prevalence of scleroderma was estimated to be 27.6 cases per 100,000 individuals in the united states.[1]
- The prevalence of scleroderma is approximately 24 cases per 100,000 individuals in the United States.[2]
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
- The standardized mortality ratio of scleroderma is approximately 1.5 to 7.2[3]
Age
- Scleroderma commonly affects individuals between 20 to 50 years of age.[4]
- Scleroderma can also occur in patients younger than 20 years or older than 50 years.
Race
- Choctaw native americans from southeastern Oklahoma were reported to have much higher prevalence of scleroderma than the general population.[5]
- Scleroderma usually affects individuals of the African-American race more than the caucasian race.[6][7]
Gender
- Females are more commonly affected by scleroderma than males. The female to male ratio is approximately ranging from 3:1 to 14:1.[7][8]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 1.2 Chifflot H, Fautrel B, Sordet C, Chatelus E, Sibilia J (February 2008). "Incidence and prevalence of systemic sclerosis: a systematic literature review". Semin. Arthritis Rheum. 37 (4): 223–35. doi:10.1016/j.semarthrit.2007.05.003. PMID 17692364.
- ↑ 2.0 2.1 Mayes MD (May 2003). "Scleroderma epidemiology". Rheum. Dis. Clin. North Am. 29 (2): 239–54. PMID 12841293.
- ↑ Ioannidis JP, Vlachoyiannopoulos PG, Haidich AB, Medsger TA, Lucas M, Michet CJ, Kuwana M, Yasuoka H, van den Hoogen F, Te Boome L, van Laar JM, Verbeet NL, Matucci-Cerinic M, Georgountzos A, Moutsopoulos HM (January 2005). "Mortality in systemic sclerosis: an international meta-analysis of individual patient data". Am. J. Med. 118 (1): 2–10. doi:10.1016/j.amjmed.2004.04.031. PMID 15639201.
- ↑ Alba MA, Velasco C, Simeón CP, Fonollosa V, Trapiella L, Egurbide MV, Sáez L, Castillo MJ, Callejas JL, Camps MT, Tolosa C, Ríos JJ, Freire M, Vargas JA, Espinosa G (March 2014). "Early- versus late-onset systemic sclerosis: differences in clinical presentation and outcome in 1037 patients". Medicine (Baltimore). 93 (2): 73–81. doi:10.1097/MD.0000000000000018. PMC 4616306. PMID 24646463.
- ↑ Arnett FC, Howard RF, Tan F, Moulds JM, Bias WB, Durban E, Cameron HD, Paxton G, Hodge TJ, Weathers PE, Reveille JD (August 1996). "Increased prevalence of systemic sclerosis in a Native American tribe in Oklahoma. Association with an Amerindian HLA haplotype". Arthritis Rheum. 39 (8): 1362–70. PMID 8702445.
- ↑ Reveille JD (April 2003). "Ethnicity and race and systemic sclerosis: how it affects susceptibility, severity, antibody genetics, and clinical manifestations". Curr Rheumatol Rep. 5 (2): 160–7. PMID 12628048.
- ↑ 7.0 7.1 Mayes MD, Lacey JV, Beebe-Dimmer J, Gillespie BW, Cooper B, Laing TJ, Schottenfeld D (August 2003). "Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population". Arthritis Rheum. 48 (8): 2246–55. doi:10.1002/art.11073. PMID 12905479.
- ↑ "Systemic scleroderma - Genetics Home Reference".