Churg-Strauss syndrome other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Other Diagnostic Studies

The following studies can be helpful in diagnosing eosinophilic granulomatosis with polyangiitis.

• Bronchoalveolar lavage:
  • Shows marked eosinophilia. Presence of marked eosinophilia on bronchoalveolar lavage is not specific for the diagnosis of eosinophilic granulomatosis with polyangiitis.
• Biopsy
  • Because of the multiple organ involvements, the biopsy should be obtained from any of the following organ sites:
    • Lung: surgical/transbronchial biopsy
    • Skin
    • Nerve
    • Kidney
    • Muscle
  • Biopsy findings may include eosinophilic infiltration, vasculitis of small and medium-sized vessels and granuloma formation.