Adult-onset Still's disease classification
Template:Adult-onset Still's disease
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
Classification based on clinical presentation
Adult-onset Stiil's disease (AOSD) may be classified based on the predominant clinical picture with which the patient presents. The following are the sub-types:[1][2]
- ASOD with pre-dominant systemic symptoms
- ASOD with pre-dominant arthritis
| Adult-onset Still's disease sub-types | Systemic sub-type | Distinguishing features | ||||
|---|---|---|---|---|---|---|
| Pre-dominant cellular mechanism | Clinical presentation | Cytokine profile | Response to treatment | Miscellaneous | ||
|
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| Arthritis sub-type | ||||||
References
- ↑ Villanueva J, Lee S, Giannini EH, Graham TB, Passo MH, Filipovich A, Grom AA (2005). "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome". Arthritis Res. Ther. 7 (1): R30–7. doi:10.1186/ar1453. PMC 1064882. PMID 15642140.
- ↑ Lee SJ, Cho YN, Kim TJ, Park SC, Park DJ, Jin HM, Lee SS, Kee SJ, Kim N, Yoo DH, Park YW (September 2012). "Natural killer T cell deficiency in active adult-onset Still's Disease: correlation of deficiency of natural killer T cells with dysfunction of natural killer cells". Arthritis Rheum. 64 (9): 2868–77. doi:10.1002/art.34514. PMID 22605480.