Reactive arthritis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
- Reactive arthritis is generally seen with preceeding GI or GU infections. Antibiotics may be given if there is an ongoing infection, but generally patients of reactive arthritis are not advised antibiotic therapy. Recent studies have shown that antibiotic therapy does not alter the course of disease and their role is not completely established.[1]
- Pharmacologic medical therapies for reactive arthritis include symptomatic control:
- 1.1 NSAIDs such as the COX-2 inhibitors
- Preferred regimen (1): Naproxen 500 mg PO q8-12h daily.
- Preferred regimen (2): Diclofenac 50 mg PO q8h daily.
- Preferred regimen (3): Indomethacin 50 mg PO q6-8h daily.
- Note(1):NSAIDs are usually given for a duration of two weeks
- Note(1):NSAIDs are contraindicated in patients with GI bleeding, heart disease and renal disease.
- 1.1 NSAIDs such as the COX-2 inhibitors
and If patients does not have
Antimicrobial regimen
References
- ↑ Barber CE, Kim J, Inman RD, Esdaile JM, James MT (June 2013). "Antibiotics for treatment of reactive arthritis: a systematic review and metaanalysis". J. Rheumatol. 40 (6): 916–28. doi:10.3899/jrheum.121192. PMID 23588936.