Churg-Strauss syndrome (patient information)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Eosinophilic granulomatosis with polyangiitis previously called Churg-Strauss syndrome is a small and medium-sized necrotizing vasculitis, with extravascular granuloma formation. The etiology is not known. However, various environmental factors, allergens, genetics, and drugs may play a role in triggering disease process by activating eosinophils, B and T lymphocytes and macrophages. The disease is characterized by the presence of asthma, peripheral eosinophilia, rhinosinusitis, peripheral neuropathy and multiple organ involvements including skin, GI tract, and kidney.
What are the symptoms of Churg-Strauss syndrome
What causes Churg-Strauss syndrome?
There are no established causes for eosinophilic granulomatosis with polyangiitis. However, various allergens, infections, vaccinations and drugs may act as a triggering agents, and are responsible for developing disease. Genetics may also play a role.