Microscopic polyangiitis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
The prevalence of Microscopic polyangiitis ranges from 1 to 3 per 100,000 a year, with higher prevalence rates occurring in Southern European countries and Asia. The incidence of the disease is 5.9 per million a year in the United Kingdom.The incidence of GPA was similar to that of MPA.MPO‐ANCAs when positive in a patient were a marker of poor prognosis in the population of patients with AAV.
Epidemiology
Prevalence
The prevalence of Microscopic polyangiitis is ranges form 1 to 3 per 100,000 persons per year.
Incidence
Microscopic polyangiitis in Europe is seen with higher incidences in Southern countries than in Northern countries. [1]
The incidence of Microscopic polyangiitis is estimated to be 5.9 per million persons per year in the United Kingdom.[2]
The incidence rate in the United States is estimated to be 3.6 per million persons.
During the last two decades the incidences of Microscopic polyangiitis has increased, which is due to the availability of testing for ANCA.
Prevalence
The prevalence of Microscopic polyangiitis is ranges from 1 to 3 per 100,000 persons per year.
Demographics
The rate of distribution of Microscopic polyangiitis varies upom age, sex, and race.
Age
- The incidence of Microscopic polyangiitis increases with age; the median age at diagnosis is 60 years.[3]
Gender
Males are more commonly affected with Microscopic polyangiitis than females (1.8:1).
Race
Microscopic polyangiitis tends to affect individuals of Asian and Southern European descent.
References
- ↑ Chung SA, Seo P (2010). "Microscopic polyangiitis". Rheum Dis Clin North Am. 36 (3): 545–58. doi:10.1016/j.rdc.2010.04.003. PMC 2917831. PMID 20688249.
- ↑ Watts RA, Mooney J, Skinner J, Scott DG, Macgregor AJ (2012). "The contrasting epidemiology of granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitis". Rheumatology (Oxford). 51 (5): 926–31. doi:10.1093/rheumatology/ker454. PMC 3465699. PMID 22258386.
- ↑ Mohammad, A. J.; Jacobsson, L. T. H.; Mahr, A. D.; Sturfelt, G.; Segelmark, M. (2007). "Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg Strauss syndrome within a defined population in southern Sweden". Rheumatology. 46 (8): 1329–1337. doi:10.1093/rheumatology/kem107. ISSN 1462-0324.