Amyloidosis natural history, complications and prognosis

Amyloidosis Microchapters
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Classification • Primary amyloidosis • Secondary amyloidosis • Familial amyloidosis • Wild-type (senile) amyloidosis • Cardiac amyloidosis • Beta-2 microglobulin related amyloidosis • Gelsolin related amyloidosis • Lysozyme amyloid related amyloidosis • Leucocyte cell-derived chemotaxin 2 related amyloidosis • Fibrinogen A alpha-chain associated amyloidosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Prognosis

• The median survival of patients with AL amyloidosis is aproximately 3.8 years.
• In AL amyloidosis 27% of patients dying within 1 year from diagnosis.
• The major determinant of outcome in amyloidosis is the extent of cardiac involvement.
  • Cardiac amyloidosis is the cause of death in 75% of the patients who died, including sudden death in 25%.

References

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