Amyloidosis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
Pathophysiology
Systemic Amyloidosis
- Amyloid is an abnormal extracellular fibrillar protein that deposit in the tissues and causes disturbance of organ function and a wide variety of clinical syndromes that are classified according to the respective fibril protein precursor.[1]
- In systemic amyloidosis, amyloid deposition is widespread and amyloid typically accumulate gradually.
Primary/Hereditary Amyloidosis
Secondary Amyloidosis
Organ-specific Amyloidosis
Gross Pathology
Microscopic Pathology
Other Diseases Associated with the Amyloid Protein
Serum Amyloid P Component
References
- ↑ Gillmore JD, Hawkins PN (October 2013). "Pathophysiology and treatment of systemic amyloidosis". Nat Rev Nephrol. 9 (10): 574–86. doi:10.1038/nrneph.2013.171. PMID 23979488.