Amyloidosis history and symptoms

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Classification • Primary amyloidosis • Secondary amyloidosis • Familial amyloidosis • Wild-type (senile) amyloidosis • Cardiac amyloidosis • Beta-2 microglobulin related amyloidosis • Gelsolin related amyloidosis • Lysozyme amyloid related amyloidosis • Leucocyte cell-derived chemotaxin 2 related amyloidosis • Fibrinogen A alpha-chain associated amyloidosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

Symptoms depend upon the organs that are affected by the amyloid deposits. These organs can include the intestines, skeletal muscles, smooth muscles, nerves, skin, ligaments, heart, liver, spleen, and kidneys.

History and Symptoms

Common Symptoms

Symptoms depend on the organs affected by the deposits. These organs can include the tongue, intestines, skeletal and smooth muscles, nerves, skin, ligaments, heart, liver, spleen, and kidneys.

Common symptoms in patients with primary amyloidosis include:

• Dyspnea
• Lethargy
• Weight loss
• Bleeding tendency
• Swelling of lower limbs
• Frothy urine
• Orthostatic hypotension
• Peripheral neuropathy