Amyloidosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

Symptoms depend upon the organs that are affected by the amyloid deposits. These organs can include the intestines, skeletal muscles, smooth muscles, nerves, skin, ligaments, heart, liver, spleen, and kidneys.

History and Symptoms

In amyloidosis, the range of symptoms depends on specific tissues and organs involvement.^[1]

History

Patients with amyloidosis may have a positive history of:^[2]

Dyspnea
Lethargy
Weight loss

Common Symptoms

Common symptoms in patients with primary amyloidosis include:^[2]

Bleeding tendency
Swelling of lower limbs
Frothy urine

Less Common Symptoms

References

↑ Jerzykowska S, Cymerys M, Gil LA, Balcerzak A, Pupek-Musialik D, Komarnicki MA (2014). "Primary systemic amyloidosis as a real diagnostic challenge - case study". Cent Eur J Immunol. 39 (1): 61–6. doi:10.5114/ceji.2014.42126. PMC 4439975. PMID 26155101.
↑ ^2.0 ^2.1 Mahmood S, Palladini G, Sanchorawala V, Wechalekar A (February 2014). "Update on treatment of light chain amyloidosis". Haematologica. 99 (2): 209–21. doi:10.3324/haematol.2013.087619. PMC 3912950. PMID 24497558.

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[pmid26155101-1] Jerzykowska S, Cymerys M, Gil LA, Balcerzak A, Pupek-Musialik D, Komarnicki MA (2014). "Primary systemic amyloidosis as a real diagnostic challenge - case study". Cent Eur J Immunol. 39 (1): 61–6. doi:10.5114/ceji.2014.42126. PMC 4439975. PMID 26155101.

[pmid24497558-2] 2.0 ^2.1 Mahmood S, Palladini G, Sanchorawala V, Wechalekar A (February 2014). "Update on treatment of light chain amyloidosis". Haematologica. 99 (2): 209–21. doi:10.3324/haematol.2013.087619. PMC 3912950. PMID 24497558.

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