Undifferentiated connective tissue disease physical examination

	Undifferentiated connective tissue disease Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Undifferentiated connective tissue disease from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
CT
MRI
Other imaging findings
Other diagnostic studies
Treatment
Medical Therapy
Surgery
Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Undifferentiated connective tissue disease physical examination On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Undifferentiated connective tissue disease physical examination All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Undifferentiated connective tissue disease physical examination
CDC on Undifferentiated connective tissue disease physical examination
Undifferentiated connective tissue disease physical examination in the news
Blogs on Undifferentiated connective tissue disease physical examination
Directions to Hospitals Treating Undifferentiated connective tissue disease
Risk calculators and risk factors for Undifferentiated connective tissue disease physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

Patients with UCTD usually appear well but can present with low-grade fever, Raynaud's phenomenon, rash and Erythema nodosum in the skin examination. On examining HEENT,Conjunctivitis, Uveitis, Keratoconjunctivitis sicca , dry-mouth can be seen. In the neck, lymphadenopathy can be seen. Rhonchi, Wheezing , pleural friction rub and Pericardial friction rub can be heard on auscultation.On examining abdomen, tenderness in the right/left upper/lower abdominal quadrant and hepatomegaly are noted. In the back, tenderness over lumbar vertebrae can occur and sacral edema may be seen.Rashes can be seen in the genitourinary exam. The patient can have altered mental status with psychosis and peripheral neuropathy and Pitting/non-pitting edema of the lower extremities.

The presence of following findings on physical examination is highly suggestive of undifferentiated connective tissue disease(UCTD):^[1]^[2]^[3]

↑ Bodolay E, Csiki Z, Szekanecz Z, Ben T, Kiss E, Zeher M, Szücs G, Dankó K, Szegedi G (2003). "Five-year follow-up of 665 Hungarian patients with undifferentiated connective tissue disease (UCTD)". Clin. Exp. Rheumatol. 21 (3): 313–20. PMID 12846049.
↑ Mosca M, Tani C, Neri C, Baldini C, Bombardieri S (November 2006). "Undifferentiated connective tissue diseases (UCTD)". Autoimmun Rev. 6 (1): 1–4. doi:10.1016/j.autrev.2006.03.004. PMID 17110308.
↑ Mosca M, Neri R, Bombardieri S (1999). "Undifferentiated connective tissue diseases (UCTD): a review of the literature and a proposal for preliminary classification criteria". Clin. Exp. Rheumatol. 17 (5): 615–20. PMID 10544849.