Glanzmann's thrombasthenia physical examination

	Glanzmann's thrombasthenia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with Glanzmann’s thrombasthenia may be asymptomatic, or they could manifest mucosal bleeding, ecchymoses,petechiae and purpura or current bleeding on physical exam.^[1]

Physical examination

Appearance of the Patient

Patient appears well in the the absence of severe hemorrhage
Patient appears ill in the persistent bleeding .

Vital Signs

may haveTachycardia, depends on the severity of the bleeding.
may haveTachypnea depends on severity of the bleeding

Skin

Cyanosis
Pallor
- Secondary to anemia
Ecchymoses,petechiae and purpura
- Secondary to thrombocytopenia

HEENT

Abnormalities of the head may include
Evidence of trauma
pale conjunctiva
Epistaxis
palatal petechiae,
gingival or other oral bleeding.

Neck

No specific sign.

Lungs

commonly normal lung sounds.

Heart

commonly normal heart sounds

Abdomen

The spleen is usually non palpable.

Neuromuscular

Patient is usually oriented to persons, place, and time
Glasgow coma scale is normally 15 / 15 but may may present loss of consciousness in severe fatal hemorrhage episodes. ^[2]