Pseudotumor cerebri risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Risk Factors
The most potent risk factors in the development of IHH are:
Common risk factors
Age and gender
Most of the IIH cases happen in women in child bearing age (9 uptodate), but it can also happens in children and old adult with male gender. In prepubertal age the gender is not an important risk factor and in old patients the percent of affected males was higher than females.(16-29 uptodate)
Obesity
Some evidences suggest that onesity can increase intra abdominal and intra cranial pressure and have a role in pathogenesis of IHH.(89)
Positive family history (15 upto)
Medications
- growth hormones: Development of IIH in result of GH therapy mostly happens in one year of medication initiation, but it can also develop after several years of treatment. witj stoping the use of GH, symptoms of IIH will improve.(35-38 upto)
- Minocycline(39)
- Doxycycline(39)
- vitamin A(39)
Systemib illness
- Addison disease(68)
- Hypoparathyroidism(69)
- Sever anemia(14)
- Sleep apnea(14)
- SLE(75)
- Behcet’s syndrome(78)
- Polycystic ovary syndrome(80)
- Coagulation disorders(80)
- Uremia(84)
Less common risk factors
drugs such as:
- thyroxin(23)
- corticosteroid withdrawal(29)
- lithium(60)
- nalidixic acid(24)
- nitrofurantoin(65)