Hydronephrosis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include Hyperkalemia, Metabolic acidosis, and Distal renal tubular acidosis.
OR
Prognosis is generally excellent, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of hydronephrosis include:[1][2][3]
- Infection secondary to obstruction
- Electrolyte imbalance
- Hyperkalemia
- Metabolic acidosis
- Distal renal tubular acidosis
- Excessive freewater diuresis
- Hypertension
- Real insufficiency and renal failure
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Kozeny GA, Hurley RM, Vertuno LL, Bansal VK, Zeller WP, Hano JE (1986). "Hypertension, mineralocorticoid-resistant hyperkalemia, and hyperchloremic acidosis in an infant with obstructive uropathy". Am. J. Nephrol. 6 (6): 476–81. doi:10.1159/000167258. PMID 3565506.
- ↑ Chandar J, Abitbol C, Zilleruelo G, Gosalbez R, Montané B, Strauss J (February 1996). "Renal tubular abnormalities in infants with hydronephrosis". J. Urol. 155 (2): 660–3. PMID 8558697.
- ↑ Lee JH, Choi HS, Kim JK, Won HS, Kim KS, Moon DH, Cho KS, Park YS (April 2008). "Nonrefluxing neonatal hydronephrosis and the risk of urinary tract infection". J. Urol. 179 (4): 1524–8. doi:10.1016/j.juro.2007.11.090. PMID 18295269.