Glucose-6-phosphate dehydrogenase deficiency risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
There are no established risk factors for [disease name].
OR
The most potent risk factor in the development of [disease name] is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.
Risk Factors
The most potent risk factor in the development of [disease name] is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].
OR
Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
Common Risk Factors
- Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.
- Common risk factors in the development of G6PD include:
- Foods such as fava beans in G6PD mutation carriers
- Medications such as:
- Aspirin,
- Antimalarials: quinine, primaquine, pamaquine, and chloroquine
- Sulfonamides: mafenide, sulfanilamide, sulfamethoxazole
- Thiazolesulfone
- Methylene blue,
- Analgesics: phenazopyridine and acetanilide
- Rasburicase
- Some non-sulfa antibiotics : furazolidone, isoniazid, dapsone, nalidixic acid, nitrofurantoin). Henna has been known to cause hemolytic crisis in G6PD-deficient infants. Rasburicase is also contraindicated in G6PD deficiency. High dose intravenous vitamin C has also been known to cause haemolysis in G6PD deficiency carriers, thus G6PD deficiency testing is routine before infusion of doses of 25g or more.
- Bacterial or viral infection
- Some chemicals: Hanna in tattos and hair dyes.[1]
Less Common Risk Factors
- Less common risk factors in the development of G6PD include:
- Moth balls (naphthalene)
- Diabetic ketoacidosis[2]
References
- ↑ Raupp P, Hassan JA, Varughese M, Kristiansson B (November 2001). "Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency". Arch. Dis. Child. 85 (5): 411–2. PMC 1718961. PMID 11668106.
- ↑ Gellady AM, Greenwood RD (June 1972). "G-6-PD hemolytic anemia complicating diabetic ketoacidosis". J. Pediatr. 80 (6): 1037–8. PMID 4623682.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [4]
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Overview
Risk Factors
- Ethnic groups
- African American
- Middle Eastern decent, particularly Kurdish or Sephardic Jewish
- Male
- Family history of the deficiency