Thrombotic thrombocytopenic purpura classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Abdurahman Khalil, M.D. [2] Sogand Goudarzi, MD [3]

Classification

TTP may be classified into several subtypes based on:

1. autoantibody against ADAMTS13

Congenital TTP Inherited TTP familial TTP Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34

1. gene mutations of ADAMTS13

References

Template:WHTemplate:WSEditor-In-Chief: C. Michael Gibson, M.S., M.D. [4]Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[5]

References

• Hereditary:
• Congenital TTP
• Inherited TTP
• familial TTP
• Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 .

• Acquired: Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.