Ameloblastoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]
Overview
The incidence of ameloblastoma is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively worldwide. Ameloblastoma affects men and women equally. There is no racial predilection to the ameloblastoma. Ameloblastoma usually occur in middle age group i.e. 20-40 years: the median age at diagnosis is 39 years.
Epidemiology and Demographics
Incidence
- The incidence of ameloblastoma is approximately 0.5 new cases in 1,000,000 people worldwide.[1]
Gender
- Ameloblastoma affects men and women equally. Although, women tend to be 4 years younger than men when tumors first occur and tumors appear to be larger in females.[2]
- The male to female ratio is approximately 1.2:1.[3]
Race
- There is no racial predilection to the ameloblastoma. However, there is conflicting evidence on the incidence rates in different races.
- Although some reports claim an increased incidence of ameloblastoma in black individuals, a large study identifies Asians as the population with greatest number of affected patients.
- Ameloblastoma is by far the most common unequivocal odontogenic neoplasm in all ethnic groups, representing approximately 1% of head and neck neoplasms in Europe and the USA, some studies claim that it has the highest incidence in Afro-Caribbean populations.[4]
Age
- Ameloblastoma commonly affects adults than younger people, the median age at diagnosis is 39 years.
- They are slow growing and tend to present in the 3rd to 5th decades of life.
- Maxillary and extraosseous ameloblastoma commonly affects individuals in a slightly older age group while unicystic and granular cell ameloblastoma occur in a younger age group.
- The average age of unicystic ameloblastoma is 10.8 years.
Region
- The majority of ameloblastoma cases are reported in Africa, China and India.[5][6]
References
- ↑ Kreppel, M; Zöller, J (2018). "Ameloblastoma-Clinical, radiological, and therapeutic findings". Oral Diseases. 24 (1–2): 63–66. doi:10.1111/odi.12702. ISSN 1354-523X.
- ↑ Toledo-Pereyra LH, Bergren CT (1987). "Liver preservation techniques for transplantation". Artif Organs. 11 (3): 214–23. PMID 3304226.
- ↑ Kreppel, M; Zöller, J (2018). "Ameloblastoma-Clinical, radiological, and therapeutic findings". Oral Diseases. 24 (1–2): 63–66. doi:10.1111/odi.12702. ISSN 1354-523X.
- ↑ Morgan, Peter R. (2011). "Odontogenic tumors: a review". Periodontology 2000. 57 (1): 160–176. doi:10.1111/j.1600-0757.2011.00393.x. ISSN 0906-6713.
- ↑ Bzhalava D, Eklund C, Dillner J (February 2015). "International standardization and classification of human papillomavirus types". Virology. 476: 341–344. doi:10.1016/j.virol.2014.12.028. PMID 25577151.
- ↑ Lu Y, Xuan M, Takata T, Wang C, He Z, Zhou Z, Mock D, Nikai H (December 1998). "Odontogenic tumors. A demographic study of 759 cases in a Chinese population". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 86 (6): 707–14. PMID 9868729.