Palmar plantar erythrodysesthesia causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Several different Chemotherapeutic agents have been associated with acral erythema

Causes

Commonly associated chemotherapeutic agents are listed below:

• Most frequently associated with Doxorubicin (Pegylated liposomal Doxorubicin), 5-Flurouracil, and Cytarabine .
• Methotrexate - even low dose used to treat ALL
• Mitotane
• PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib

Genetics

No genetic association has been found as of yet as the data on this condition is limited.