Myelofibrosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Myelofibrosis is a rare disorder and its common risk factors may be age, other myeloproliferative disorders, radiation, or industrial chemical exposure.
Risk Factors
Common risk factors in the development of myelofibrosis include:
- Age: Myelofibrosis most commonly affects individuals in their 50s and 60s.
- Other myeloproliferative disorder: Myelofibrosis may also develop secondary to essential thrombocythemia or polycythemia vera.
- Radiation exposure: Individuals exposed to high levels of radiation (e.g. Thorotrast) have an increased risk of myelofibrosis.
- Chemicals: Industrial chemicals, such as toluene and benzene, may have an increased risk of developing myelofibrosis.