Hepatocellular adenoma causes

Hepatocellular adenoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]

Causes

• The causes of hepatocellular adenoma include;
  • Oral contraceptive medications
    • The causal relationship is proportional to the hormonal dose and duration of medication, highest in women over 30 years of age and after 24 months of using oral contraceptives.
  • Pregnancy
    • It appears to stimulate rapid growth in these lesions with the risk of potentially fatal spontaneous rupture.
  • Glycogen storage disease types I,II and IV
  • Long term use of anabolic androgenic steroids
  • Metabolic syndrome
  • Maturity onset diabetes of young (MODY)
  • Obesity
  • Clomiphene
  • Familial adenomatous polyposis
  • Vascular disorders such as portal vein agenesis, budd chiari syndrome and hereditary hemorrhagic telangiectasia.

References

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