Splenic marginal zone lymphoma medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

The predominant therapy for splenic marginal zone lymphoma is surgery. Adjunctive radiotherapy, chemotherapy, and biological therapy may be required. The optimal therapy for splenic marginal zone lymphoma depends on the clinical presentation.

Medical Therapy

The predominant therapy for splenic marginal zone lymphoma is surgery. Adjunctive radiotherapy, chemotherapy, and biological therapy may be required. The optimal therapy for splenic marginal zone lymphoma depends on the clinical presentation.

Treatment of splenic marginal zone lymphoma[1]
Therapy Description
Watchful waiting People may not need treatment right away unless they have symptoms
Splenectomy Often respond very well when their spleen is removed with surgery
Radiation Therapy When a splenectomy is not an option, external beam radiation therapy to the spleen
Chemotherapy Doesn’t respond well to chemotherapy
Biological therapy Rituximab may be used alone or in combination with chemotherapy

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