Sarcomatoid carcinoma of the lung screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Overview

Screening is a strategy used to identify early lung cancer in people, before they develop symptoms. Screening studies for lung cancer have only been done in high risk populations, such as smokers and workers with occupational exposure to certain substances. This is because radiation exposure from screening could actually induce carcinogenesis cancer formation in a small percentage of screened subjects, so this risk should be mitigated by a (relatively) high prevalence of lung cancer in the population being screened. A pulmonary nodule larger than 5 to 6 mm is considered a positive result for screening with x-ray or computed tomography.

Practice Guidelines

Current Guidelines

  • In 2013, a clinical practice guideline by the U.S. Preventive Services Task Force (USPSTF) recommended screening for lung cancer among smokers and former smokers who are between 55 to 80 years old and who have smoked 30 pack-years or more and either continue to smoke or have quit within the past 15 years (grade B recommendation).[1]
  • Clinical practice guidelines issued by the American College of Chest Physicians in 2013 recommend:[2] [3][4]
    • For smokers and former smokers who are age 55 to 74 and who have smoked for 30 pack-years or more and either continue to smoke or have quit within the past 15 years, it was suggest that annual screening with low dose computed tomography (LDCT) should be offered in settings that can deliver the comprehensive care provided to National Lung Screening Trial (NLST) participants.

Screening for Lung Cancer U.S. Preventive Services Task Force Recommendation Statement 2013 [1]

"1. The USPSTF recommends annual screening for lung cancer with low-dose computed tomography (LDCT) in adults aged 55 to 80 years who have a 30 pack-year smoking history and currently smoke or have quit within the past 15 years. Screening should be discontinued once a person has not smoked for 15 years or develops a health problem that substantially limits life expectancy or the ability or willingness to have curative lung surgery. (Grade B)"

References

  1. 1.0 1.1 "http://www.uspreventiveservicestaskforce.org/uspstf13/lungcan/lungcanfinalrs.htm". Retrieved 31 December 2013. External link in |title= (help)
  2. Detterbeck FC, Mazzone PJ, Naidich DP, Bach PB (2013). "Screening for Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 143 (5 Suppl): e78S–92S. doi:10.1378/chest.12-2350. PMID 23649455. Summary in JournalWatch
  3. Midthun, David E. (2016). "Early detection of lung cancer". F1000Research. 5: 739. doi:10.12688/f1000research.7313.1. ISSN 2046-1402.
  4. Midthun, David E. (2011). "Screening for Lung Cancer". Clinics in Chest Medicine. 32 (4): 659–668. doi:10.1016/j.ccm.2011.08.014. ISSN 0272-5231.


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